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1. (WO2018018018) METHODS FOR THE TREATMENT OF CANCER USING COENZYME Q10 IN COMBINATION WITH IMMUNE CHECKPOINT MODULATORS

Pub. No.:    WO/2018/018018    International Application No.:    PCT/US2017/043396
Publication Date: Fri Jan 26 00:59:59 CET 2018 International Filing Date: Sat Jul 22 01:59:59 CEST 2017
IPC: A61K 31/122
A61K 45/06
A61P 35/02
C07K 16/32
G01N 33/53
Applicants: BERG LLC
Inventors: NASTKE, Maria-Dorothea
KAZEROUNIAN, Shiva
DIERS, Anne, R.
VISHNUDAS, Vivek, K.
GESTA, Stephane
SARANGARAJAN, Rangaprasad
NARAIN, Niven, Rajin
Title: METHODS FOR THE TREATMENT OF CANCER USING COENZYME Q10 IN COMBINATION WITH IMMUNE CHECKPOINT MODULATORS
Abstract:
Presented herein are methods for the treatment of oncological disorders by the co- administration of Coenzyme QI0 and immune checkpoint modulators. The Coenzyme QI0 formulations may be at least one of intravenous, topical, or by inhalation. Co-administration of the Coenzyme QI0 formulations may be prior to, concurrent or substantially concurrent with, intermittent with or subsequent to the administration of the chemotherapy.