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1. (WO2018017983) COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO RET
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/017983 International Application No.: PCT/US2017/043340
Publication Date: 25.01.2018 International Filing Date: 21.07.2017
IPC:
C07D 401/14 (2006.01)
Applicants: BLUEPRINT MEDICINES CORPORATION[US/US]; 38 Sidney Street Suite 200 Cambridge, Massachusetts 02139, US
Inventors: BRUBAKER, Jason D.; US
GUZI, Timothy; US
WILSON, Kevin J.; US
DIPIETRO, Lucian V.; US
ZHANG, Yulian; US
WILSON, Douglas; US
FLEMING, Paul E.; US
Agent: MACALPINE, Jill K.; US
RODRIGO, Christina, M.; US
Priority Data:
62/365,72422.07.2016US
Title (EN) COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO RET
(FR) COMPOSÉS UTILES POUR TRAITER DES TROUBLES LIÉS À RET
Abstract: front page image
(EN) Described herein are compounds of formula (I) that inhibit wild- type RET and its resistant mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.
(FR) La présente invention concerne des composés de formule (I) qui inhibent RET de type sauvage et ses mutants résistants, des compositions pharmaceutiques comprenant lesdits composés, et des méthodes d'utilisation desdits composés et desdites compositions.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)