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1. (WO2018017884) SYSTEMS AND METHODS FOR NUCLEIC ACID SEQUENCING
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Pub. No.: WO/2018/017884 International Application No.: PCT/US2017/043159
Publication Date: 25.01.2018 International Filing Date: 20.07.2017
IPC:
C12Q 1/68 (2006.01) ,G01N 27/414 (2006.01) ,G01N 33/551 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
403
Cells and electrode assemblies
414
Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
551
the carrier being inorganic
Applicants:
GENAPSYS, INC. [US/US]; 200 Cardinal Way, Third Floor Redwood City, 94063, US
Inventors:
ESFANDYARPOUR, Hesaam; US
LAU, Aldrich, N.K.; US
PARIZI, Kosar; US
PALIWAL, Saurabh; US
PERSSON, Henrik; US
STERN, Seth; US
KENNEY, Paul; US
BARMI, Meysam, R.; US
NABI, Ali; US
RATEGH, Hamid; US
OBERSTRASS, Florian; US
Agent:
ALEMOZAFAR, Ali, R.; US
AGRAWAL, Trisha; US
ALMEDA, Dariela; US
AMJADI, Nellie; US
ADVANI, Raj; US
Priority Data:
62/364,48920.07.2016US
62/375,19715.08.2016US
62/418,10104.11.2016US
62/444,70010.01.2017US
Title (EN) SYSTEMS AND METHODS FOR NUCLEIC ACID SEQUENCING
(FR) SYSTÈMES ET PROCÉDÉS DE SÉQUENÇAGE D’ACIDES NUCLÉIQUES
Abstract:
(EN) Provided herein are systems and methods for processing and analyzing nucleic acids and other biomolecules. Methods may include processing nucleic acid molecules in an emulsion of droplets. Methods of analyzing nucleic acid molecules may include coupling nucleic acids to a bead or other support. Methods may include analysis of nucleic acid molecules using a redox mediator. In some cases, analysis of the nucleic acid molecule includes determining a nucleotide sequence of the nucleic acid molecule.
(FR) La présente invention concerne des systèmes et des procédés de traitement et d’analyse d’acides nucléiques et d’autres biomolécules. Les procédés peuvent comprendre le traitement de molécules d’acide nucléique dans une émulsion de gouttelettes. Les procédés d’analyse des molécules d’acide nucléique peuvent comprendre le couplage des acides nucléiques à une bille ou à un autre support. Les procédés peuvent comprendre l’analyse des molécules d’acide nucléique à l'aide d'un médiateur rédox. Dans certains cas, l’analyse de la molécule d’acide nucléique comprend la détermination d’une séquence nucléotidique de la molécule d’acide nucléique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)