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1. (WO2018017761) MULTIMERIC CD137/4-1BB BINDING MOLECULES AND USES THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/017761    International Application No.:    PCT/US2017/042931
Publication Date: 25.01.2018 International Filing Date: 19.07.2017
IPC:
A01N 43/04 (2006.01), A61K 39/00 (2006.01), A61K 39/395 (2006.01), A61P 35/00 (2006.01), A61P 37/04 (2006.01), C07K 16/28 (2006.01)
Applicants: IGM BIOSCIENCES, INC. [US/US]; 325 Middlefield Road Mountain View, California 94043 (US)
Inventors: KEYT, Bruce Alan; (US).
BALIGA, Ramesh; (US).
WANG, Beatrice Tien-Yi; (US)
Agent: HAANES, Elizabeth J.; (US).
BRAUNEL, Matthew A.; (US).
COLVIN, Katherine E.; (US).
DAVIS, J. Wendy; (US).
BLENKE, Thaddeus J.; (US).
HIMICH, Matthew J.; (US).
VOLK, Benjamin L.; (US).
HOLTZ, William A.; (US).
JINKINS, David B.; (US).
KERCHER, Kevin M.; (US).
MOUSSAVI, Sartouk H.; (US).
MUSCH, Jonathan G.; (US).
NEPPLE, Michael L.; (US).
NORMAN, Alan H.; (US).
PARKS, Michael A.; (US).
POLCYN, Thomas A.; (US).
RITCHEY, Steven M.; (US).
ROMANO, Charles P.; (US).
SCHWENT, Jason M.; (US).
GERLACH, Robert D.; (US).
BLUM, Anthony F.; (US).
ZAK, Clayton R.; (US).
MANSE, Jared S.; (US)
Priority Data:
62/364,760 20.07.2016 US
Title (EN) MULTIMERIC CD137/4-1BB BINDING MOLECULES AND USES THEREOF
(FR) MOLÉCULES FIXANT PDK137/4 ET LEURS UTILISATIONS
Abstract: front page image
(EN)This disclosure provides dimeric, pentameric, and hexameric CD137/4-1BB agonist binding molecules and methods of using such binding molecules to induce anti-tumor immunity.
(FR)L'invention concerne des molécules fixant les agonistes CD137/4-1BB dimériques, pentamériques et hexamériques et des procédés d'utilisation de telles molécules de liaison pour induire une immunité antitumorale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)