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1. (WO2018017469) MULTIPLEX DETECTION OF INTRACELLULAR OR SURFACE MOLECULAR TARGETS IN SINGLE CELLS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/017469 International Application No.: PCT/US2017/042360
Publication Date: 25.01.2018 International Filing Date: 17.07.2017
IPC:
C12Q 1/68
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants: YALE UNIVERSITY[US/US]; Two Whitney Avenue New Haven, CT 06510, US
Inventors: FAN, Rong; US
LU, Yao; US
WANG, Nayi; US
Agent: DIPIETRANTONIO, Heather, J.; US
Priority Data:
62/363,69618.07.2016US
Title (EN) MULTIPLEX DETECTION OF INTRACELLULAR OR SURFACE MOLECULAR TARGETS IN SINGLE CELLS
(FR) DÉTECTION MULTIPLEXÉE DE CIBLES MOLÉCULAIRES INTRACELLULAIRES OU DE SURFACE DANS DES CELLULES UNIQUES
Abstract:
(EN) This disclosure demonstrates an approach that translates synthetic DNA codes to spatial codes registered in nanoliter microchambers for multiplexed measurement of nearly any type of molecular targets (e.g., miRNAs, mRNAs, intracellular and surface proteins) in single cells.
(FR) La présente invention présente une technique permettant de traduire des codes d'ADN synthétique en codes spatiaux enregistrés dans des microchambres présentant un volume de l'ordre du nanolitre, pour une mesure multiplexée de pratiquement n'importe quel type de cibles moléculaires (par exemple, des miARN, des ARNm, des protéines intracellulaires et des protéines de surface) dans des cellules uniques.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)