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|1. (WO2018016917) RECOMBINANT VACCINIA VIRUS AND USE THEREOF|
|Applicants:||KOLON LIFE SCIENCE, INC.
|Title:||RECOMBINANT VACCINIA VIRUS AND USE THEREOF|
The present invention relates to a recombinant vaccinia virus in which the expression of some genes is inhibited, and a use thereof. The recombinant vaccinia virus of the present invention selectively kills cancer cells, and has an excellent reproducibility in cancer cells. Also, the virus has a lower toxicity to normal cells, and thus has an advantage of being safe for a human body. Therefore, the recombinant vaccinia virus of the present invention can be effectively used as a composition for treating cancer.