WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2018016743) OXAZOLIDINONE DERIVATIVE COMPOUND AS CETP INHIBITOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/016743 International Application No.: PCT/KR2017/006358
Publication Date: 25.01.2018 International Filing Date: 16.06.2017
IPC:
C07D 263/20 (2006.01) ,A61K 31/421 (2006.01)
Applicants: DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION[KR/KR]; 88, Dongnae-ro Dong-gu Daegu 41061, KR
KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL[KR/KR]; 130, Dongdeok-ro Jung-gu Daegu 41944, KR
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION[KR/KR]; 80, Daehak-ro Buk-gu Daegu 41566, KR
Inventors: SONG, Minsoo; KR
LEE, Sungwoo; KR
KIM, Soong-Hyun; KR
HWANG, Hee Jong; KR
LEE, Won Seok; KR
LEE, Sang Kwang; KR
MA, Minjung; KR
LEE, Eunhye; KR
IM, Chun Young; KR
PARK, Ga Young; KR
WOO, Seo Yeon; KR
KO, Eun Bi; KR
KIM, Yong-Lim; KR
Agent: AHN, So Young; KR
Priority Data:
10-2016-009130419.07.2016KR
Title (EN) OXAZOLIDINONE DERIVATIVE COMPOUND AS CETP INHIBITOR
(FR) COMPOSÉ DÉRIVÉ D'OXAZOLIDINONE EN TANT QU'INHIBITEUR DE CETP
(KO) CETP 억제제로서의 옥사졸리딘온 유도체 화합물
Abstract:
(EN) The present invention provides an oxazolidinone derivative compound represented by chemical formula I, an optical isomer thereof, or pharmaceutically acceptable salts thereof. The compound represented by chemical formula I according to the present invention has a CETP-inhibiting effect, which leads to the effects of increasing HDL cholesterol and reducing LDL cholesterol, and a pharmaceutical composition containing the compound can be used for treating or preventing a disorder or a disease which is mediated by CETP or responds to CETP inhibition.
(FR) La présente invention concerne un composé dérivé d'oxazolidinone représenté par la formule chimique I, son isomère optique, ou ses sels pharmaceutiquement acceptables. Le composé représenté par la formule chimique I selon la présente invention a un effet inhibiteur de CETP, ce qui conduit à des effets d'augmentation du cholestérol HDL et de réduction du cholestérol LDL, et une composition pharmaceutique contenant le composé peut être utilisée pour le traitement ou la prévention d'un trouble ou d'une maladie induite par CETP ou réagit à l'inhibition du CETP.
(KO) 본 발명은 화학식 I로 표시되는 옥사졸리딘온 유도체 화합물, 이의 광학이성질체, 또는 이들의 약제학적으로 허용되는 염을 제공한다. 본 발명의 화학식 I로 표시되는 화합물은, CETP 저해 효과를 갖고, 이는 HDL-콜레스테롤을 상승시키고, LDL-콜레스테롤을 감소시키는 작용 효과를 나타내며, 이를 포함하는 약제학적 조성물은 CETP에 의해 매개되거나 CETP의 억제에 대해 반응하는 장애 또는 질환의 치료 또는 예방 용도로서 사용 가능하다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)