WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2018016645) NOVEL PHOSPHOLIPID, USES THEREOF AND DEVELOPMENT OF PHOSPHOLIPID SEPARATION AND MEASUREMENT METHOD
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/016645    International Application No.:    PCT/JP2017/026563
Publication Date: 25.01.2018 International Filing Date: 21.07.2017
IPC:
C07F 9/117 (2006.01), G01N 27/62 (2006.01), G01N 30/72 (2006.01), G01N 30/88 (2006.01), G01N 33/92 (2006.01)
Applicants: AKITA UNIVERSITY [JP/JP]; 1-1, Tegata Gakuen-Machi, Akita-shi, Akita 0108502 (JP).
AKITA LIPID TECHNOLOGIES LLC. [JP/JP]; 1-2, Nukazuka, Yanagida, Akita-shi, Akita 0100825 (JP)
Inventors: SASAKI Takehiko; (JP).
NAKANISHI Hiroki; (JP).
ISHIKAWA Masaki; (JP).
UENO Noriko; (JP).
EGUCHI Satoshi; (JP).
SASAKI Junko; (JP).
NAKANISHI Takayo; (JP)
Agent: YAMAMOTO Shusaku; (JP).
MORISHITA Natsuki; (JP).
KOMATANI Takeshi; (JP).
IIDA Takatoshi; (JP).
ISHIKAWA Daisuke; (JP).
YAMAMOTO Kensaku; (JP)
Priority Data:
2016-144177 22.07.2016 JP
2017-051354 16.03.2017 JP
Title (EN) NOVEL PHOSPHOLIPID, USES THEREOF AND DEVELOPMENT OF PHOSPHOLIPID SEPARATION AND MEASUREMENT METHOD
(FR) NOUVEAU PHOSPHOLIPIDE ET SES UTILISATIONS AINSI QUE DÉVELOPPEMENT D'UN PROCÉDÉ DE MESURE DE SÉPARATION DE PHOSPHOLIPIDES
(JA) 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発
Abstract: front page image
(EN)The present invention provides a lysophosphatidylinositol phosphate that is a novel phospholipid, and uses thereof. The present invention also provides a method for isolating and analyzing the binding site of the pohosphate group of the phospholipid. Specifically provided is a method for measuring, detecting or identifying a phospholipid in a sample, the method comprising: (A) a step for subjecting the sample to liquid column chromatography-mass spectrometry (LC-MS) or ion mobility spectrometry-mass spectrometry (IMS-MS); and (B) a step for identifying the position of the phopsphate group of the phospholipid on the basis of the peak elution position in the LC-MS.
(FR)L'invention concerne un lysophosphatidylinositol-phosphate, lequel est un nouveau phospholipide, ainsi que les utilisations de celui-ci. L'invention concerne également un procédé de séparation et d'analyse des sites de liaison d'un phospholipide. Plus spécifiquement, le procédé selon l'invention permet de mesurer, détecter ou identifier un phospholipide dans un échantillon, et comporte: (A) une étape dans laquelle une analyse par chromatographie liquide sur colonne - spectrométrie de masse (LC-MS) ou une analyse par spectrométrie de mobilité ionique - spectrométrie de masse (IMS-MS) est appliquée à un échantillon; et (B) une étape dans laquelle en fonction de la position d'élution de pics en LC-MS, la position du groupe phosphate du phospholipide est identifiée.
(JA)本発明は、新規リン脂質であるリゾホスファチジルイノシトールリン酸塩およびその利用を提供する。本発明はまた、リン脂質のリン酸基結合位置を分離して分析する方法を提供する。詳細には、本発明は、試料中のリン脂質を測定、検出または同定する方法であって、該方法はA)該試料を液体カラムクロマトグラフィー-質量分析(LC-MS)またはイオンモビリティ分離-質量分析(IMS-MS)に適用する工程;およびB)該LC-MSにおけるピークの溶出位置により該リン脂質のリン酸基の位置を特定する工程を包含する、方法を提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)