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1. (WO2018016645) NOVEL PHOSPHOLIPID, USES THEREOF AND DEVELOPMENT OF PHOSPHOLIPID SEPARATION AND MEASUREMENT METHOD

Pub. No.:    WO/2018/016645    International Application No.:    PCT/JP2017/026563
Publication Date: Fri Jan 26 00:59:59 CET 2018 International Filing Date: Sat Jul 22 01:59:59 CEST 2017
IPC: C07F 9/117
G01N 27/62
G01N 30/72
G01N 30/88
G01N 33/92
Applicants: AKITA UNIVERSITY
国立大学法人秋田大学
AKITA LIPID TECHNOLOGIES LLC.
Akita Lipid Technologies合同会社
Inventors: SASAKI Takehiko
佐々木 雄彦
NAKANISHI Hiroki
中西 広樹
ISHIKAWA Masaki
石川 将己
UENO Noriko
上野 紀子
EGUCHI Satoshi
江口 賢史
SASAKI Junko
佐々木 純子
NAKANISHI Takayo
中西 貴代
Title: NOVEL PHOSPHOLIPID, USES THEREOF AND DEVELOPMENT OF PHOSPHOLIPID SEPARATION AND MEASUREMENT METHOD
Abstract:
The present invention provides a lysophosphatidylinositol phosphate that is a novel phospholipid, and uses thereof. The present invention also provides a method for isolating and analyzing the binding site of the pohosphate group of the phospholipid. Specifically provided is a method for measuring, detecting or identifying a phospholipid in a sample, the method comprising: (A) a step for subjecting the sample to liquid column chromatography-mass spectrometry (LC-MS) or ion mobility spectrometry-mass spectrometry (IMS-MS); and (B) a step for identifying the position of the phopsphate group of the phospholipid on the basis of the peak elution position in the LC-MS.