WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2018015971) AN IMPROVED PROCESS FOR THE PREPARATION OF DEXMETHYL PHENIDATE HYDROCHLORIDE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/015971 International Application No.: PCT/IN2017/050293
Publication Date: 25.01.2018 International Filing Date: 17.07.2017
IPC:
C07D 211/22 (2006.01)
Applicants: HARMAN FINOCHEM LIMITED[IN/IN]; 107, Vinay Bhavya Complex 159 –A, C.S.T. Road, Kalina, Mumbai, Maharashtra 400098, IN
Inventors: KADAM, Vijay Trimbak; IN
SARANAPU, Nareesh; IN
CHAVAN, Santosh Uttamrao; IN
MINHAS, Harpreet Singh; IN
MINHAS, Gurpreet Singh; IN
Agent: P., Aruna Sree; IN
Priority Data:
20162102451618.07.2016IN
Title (EN) AN IMPROVED PROCESS FOR THE PREPARATION OF DEXMETHYL PHENIDATE HYDROCHLORIDE
(FR) PROCÉDÉ DE PRÉPARATION AMÉLIORÉ DE L'HYDROCHLORURE DE DEXMÉTHYLE PHÉNIDATE
Abstract:
(EN) Disclosed herein a process for the preparation of highly pure dexmethylphenidate hydrochloride (Formula-I) which comprises the steps of neutralization of dl- threomethylphenidate hydrochloride to dl-threo methylphenidate; subsequent resolution of dl-threo methylphenidate using amino acid or its derivatives as chiral resolution agent to yield dexmethylphenidate salt; hydrolysis of the salt and further conversion of dexmethylphenidate into its hydrochloride salt.
(FR) L'invention concerne un procédé de préparation de l'hydrochlorure de dexméthylphénidate hautement pur (formule-I) qui comprend les étapes de neutralisation de l'hydrochlorure de dl-threométhylphénidate en dl-thréométhylphénidate; la résolution ultérieure du dl-thréométhylphénidate à l'aide d'un acide aminé ou de ses dérivés en tant qu'agent de résolution chiral pour produire le sel de dexméthylphénidate; l'hydrolyse du sel et la conversion supplémentaire du dexméthylphénidate en son sel d'hydrochlorure.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)