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1. WO2018015690 - IMPLANTABLE MEDICAL DEVICE FOR LOCOREGIONAL INJECTION

Publication Number WO/2018/015690
Publication Date 25.01.2018
International Application No. PCT/FR2017/052013
International Filing Date 21.07.2017
IPC
A61M 37/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
37Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
A61L 31/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31Materials for other surgical articles
14Materials characterised by their function or physical properties
CPC
A61M 2037/003
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
37Other apparatus for introducing media into the body
0015by using microneedles
003having a lumen
A61M 2210/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
2210Anatomical parts of the body
12Blood circulatory system
A61M 37/0015
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
37Other apparatus for introducing media into the body
0015by using microneedles
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • UNIVERSITÉ D'ANGERS [FR]/[FR]
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [FR]/[FR]
  • INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) [FR]/[FR]
Inventors
  • CALVIGNAC, Brice
  • GIMEL, Jean-Christophe
  • LEMAIRE, Laurent
  • FRANCONI, Florence
Agents
  • ICOSA
Priority Data
165695421.07.2016FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) IMPLANTABLE MEDICAL DEVICE FOR LOCOREGIONAL INJECTION
(FR) DISPOSITIF MÉDICAL IMPLANTABLE D'INJECTION LOCORÉGIONALE
Abstract
(EN)
The present invention concerns an implantable medical device (1) for locoregional injection and/or sampling in the lumen of a blood vessel or in a parenchyma, comprising a microfluidic chip (13) and a cover (14), wherein the microfluidic chip (13) comprises at least one microfluidic channel (121) extending from a first face of the microfluidic chip (13) to a second face of the microfluidic chip (13), the cover (14) comprises at least two hollow micro-needles (11) protruding from the cover (14), the cover (14) is fixed to the second surface of the microfluidic chip (13) such that the at least one microfluidic channel (121) is in fluid connection with the at least two hollow micro-needles (11); and the length of the at least two hollow micro-needles (11) projecting from the cover (14) is configured such that when the cover (14) is implanted on the outer wall of a blood vessel or on a parenchyma, the end of the at least two hollow micro-needles (11) penetrates into the lumen of the blood vessel or into the parenchyma.
(FR)
La présente invention concerne un dispositif médical implantable (1) d'injection et / ou de prélèvement locorégional dans la lumière d'un vaisseau sanguin ou dans un parenchyme comprenant une puce microfluidique (13) et un capot (14), dans lequel la puce microfluidique (13) comprend au moins un canal microfluidique (121) s 'étendant depuis une première face de la puce microfluidique (13) jusqu'à une deuxième face de la puce microfluidique (13), le capot (14) comprend au moins deux micro-aiguilles creuses (11) faisant saillie depuis le capot (14), le capot (14) est fixé sur la deuxième face de la puce microfluidique (13) de sorte que le au moins un canal microfluidique (121) soit en connexion fluide avec les au moins deux micro-aiguilles creuses (11); et la longueur des au moins deux micro-aiguilles creuses (11) faisant saillie depuis le capot (14) est configuré de sorte que lorsque le capot (14) est implanté sur la paroi externe d'un vaisseau sanguin ou sur un parenchyme, l'extrémité des au moins deux micro-aiguilles creuses (11) pénètre la lumière du vaisseau sanguin ou dans le parenchyme.
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