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1. (WO2018015196) SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE

Pub. No.:    WO/2018/015196    International Application No.:    PCT/EP2017/067273
Publication Date: Fri Jan 26 00:59:59 CET 2018 International Filing Date: Tue Jul 11 01:59:59 CEST 2017
IPC: C07D 471/08
C07D 498/08
A61K 31/439
A61K 31/5386
A61P 25/00
Applicants: BAYER AKTIENGESELLSCHAFT
BAYER PHARMA AKTIENGESELLSCHAFT
Inventors: DELBECK, Martina
HAHN, Michael
MÜLLER, Thomas
LUSTIG, Klemens
MOSIG, Johanna
ALBUS, Udo
GEHRING, Doris
ROSENSTEIN, Björn
COLLINS, Karl
LINDNER, Niels
SEELIGER, Janine
BECK-BROICHSITTER, Moritz
Title: SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE
Abstract:
The present invention relates to novel (imidazo[1,2-a]pyridine-3-yl)methyl-substituted diazahetero-bicyclic compounds, to methods for preparing same, to their use alone or in combinations for the treatment and/or prevention of diseases, as well as to their use for producing drugs for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of breathing disorders, including sleep-related breathing disorders such as obstructive and central sleep apnea and snoring. The present invention further relates to a method for detecting a compound having TASK-1 and/or TASK-3 blocking properties.