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1. (WO2018014855) MULTISPECIFIC ANTIGEN BINDING PROTEINS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/014855    International Application No.:    PCT/CN2017/093644
Publication Date: 25.01.2018 International Filing Date: 20.07.2017
IPC:
C07K 16/46 (2006.01), C07K 16/18 (2006.01), C07K 16/28 (2006.01), C07K 16/30 (2006.01), C07K 16/24 (2006.01), A61K 39/395 (2006.01), A61P 35/00 (2006.01), A61P 37/00 (2006.01)
Applicants: NANJING LEGEND BIOTECH CO., LTD. [CN/CN]; No.6 Building of Nanjing Life Science Town, No. 568 Longmian Avenue, Jiangning District Nanjing, Jiangsu 211100 (CN)
Inventors: CHOU, Chuan-Chu; (US).
ZHANG, Yafeng; (CN).
WU, Shu; (CN).
LIU, Zhenyu; (CN).
LI, Zhongdao; (CN).
ZHANG, Fangliang; (CN)
Agent: CHENG & PENG INTELLECTUAL PROPERTY LAW OFFICE; 821 Yufei Plaza, 42 Dongzhimenwai Avenue Dongcheng District Beijing 100027 (CN)
Priority Data:
PCT/CN2016/090703 20.07.2016 CN
Title (EN) MULTISPECIFIC ANTIGEN BINDING PROTEINS AND METHODS OF USE THEREOF
(FR) PROTÉINES DE LIAISON AUX ANTIGÈNES MULTISPÉCIFIQUES ET LEURS PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)Disclosed herein are multispecific, such as bispecific, antigen binding proteins comprising a first antigen binding domain comprising a heavy chain variable domain and a light chain variable domain, and a second antigen binding domain comprising a single-domain antibody. Pharmaceutical compositions comprising the multispecific antigen binding proteins, kits and methods of use thereof are further provided.
(FR)L'invention concerne des protéines de liaison aux antigènes multispécifiques, telles que les bispécifiques, comprenant un premier domaine de liaison à l'antigène comprenant un domaine variable de chaîne lourde et un domaine variable de chaîne légère, et un second domaine de liaison à l'antigène comprenant un anticorps à domaine unique. L'invention porte également sur des compositions pharmaceutiques comprenant les protéines de liaison aux antigènes multispécifiques, sur des kits et sur leurs procédés d'utilisation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)