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1. (WO2018014829) AMINOPYRIDINE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS

Pub. No.:    WO/2018/014829    International Application No.:    PCT/CN2017/093385
Publication Date: Fri Jan 26 00:59:59 CET 2018 International Filing Date: Wed Jul 19 01:59:59 CEST 2017
IPC: C07D 401/10
C07D 401/12
C07D 401/14
C07D 405/14
C07D 409/14
C07D 411/14
C07D 413/00
C07D 417/00
C07D 419/00
A61K 31/4427
A61P 19/00
Applicants: NOVARTIS AG
Inventors: LI, Jialiang
ARISTA, Luca
BABU, Sreehari
BIAN, Jianwei
CUI, Kai
DILLON, Michael Patrick
LATTMANN, Rene
LIAO, Lv
LIZOS, Dimitrios
RAMOS, Rita
STIEFL, Nikolaus Johannes
ULLRICH, Thomas
USSELMANN, Peggy
WANG, Xiaoyang
WAYKOLE, Liladhar Murlidhar
WEILER, Sven
ZHANG, Yubo
ZHOU, Yizong
ZHU, Tingying
Title: AMINOPYRIDINE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS
Abstract:
The invention relates to a compound of formula (I) in free form or in pharmaceutically acceptable salt form (I) to pharmaceutical compositions comprising said compound and to the use of said compound in the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva.