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1. (WO2018014116) SOLID FORMS OF TTK INHIBITOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/014116 International Application No.: PCT/CA2017/050848
Publication Date: 25.01.2018 International Filing Date: 13.07.2017
IPC:
C07D 487/04 (2006.01) ,A61K 31/519 (2006.01) ,A61P 35/00 (2006.01) ,C30B 7/02 (2006.01)
Applicants: UNIVERSITY HEALTH NETWORK[CA/CA]; 190 Elizabeth Street R. Fraser Elliott Building - Room 1S-417 Toronto, Ontario M5G 2C4, CA
Inventors: LI, Sze-Wan; CA
PAULS, Heinz W.; CA
SAMPSON, Peter Brent; CA
Agent: BAKER, James D.; CA
BOWN, Christopher D.; CA
NEWTON, Trevor; CA
SCHROEDER, Hans; CA
ROY, Matthew; CA
SPRIGINGS, Mark; CA
LEDWELL, M. Kent; CA
WILKIE, Jennifer; CA
Priority Data:
62/363,42418.07.2016US
Title (EN) SOLID FORMS OF TTK INHIBITOR
(FR) FORMES SOLIDES D'INHIBITEUR DE TTK
Abstract: front page image
(EN) The present invention relates to a novel co-crystal of the compound of formula (I): (Formula (I)) wherein the co-former molecule is bisphosphate hemihydrate, to processes for the preparation of the co-crystal, to pharmaceutical compositions containing the co-crystal, to the use of such a co-crystal in the manufacture of a medicament for use in the treatment of cancer and to methods of treating such diseases in the human or animal body by administering a therapeutically effective amount of such a co-crystal.
(FR) La présente invention concerne des nouveaux co-cristaux d’un composé de formule (I) dans laquelle la molécule de co-formation étant le bisphosphate hémihydrate, des procédés pour la préparation de ces co-cristaux, des compositions pharmaceutiques contenant les co-cristaux, l'utilisation desdits co-cristaux dans la fabrication d'un médicament à utiliser dans le traitement du cancer et des méthodes de traitement de ces maladies chez l’homme ou l’animal par administration d'une dose thérapeutiquement efficace desdits co-cristaux.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)