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1. (WO2018014006) COMPOSITIONS AND METHODS FOR FLAVIVIRUS VACCINATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/014006 International Application No.: PCT/US2017/042269
Publication Date: 18.01.2018 International Filing Date: 14.07.2017
IPC:
A61K 39/235 (2006.01) ,C12N 15/861 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
235
Adenoviridae
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
86
Viral vectors
861
Adenoviral vectors
Applicants: ETUBICS CORPORATION[US/US]; 410 West Harrison Street, Suite 200 Seattle, WA 98119, US
Inventors: JONES, Frank, R.; US
BALINT, Joseph; US
RICE, Adrian; US
LATCHMAN, Yvette; US
GABITZSCH, Elizabeth; US
Agent: HOLZAPFEL, Keli, L.; US
ADVANI, Raj; US
ALMEDA, Dariela; US
AGRAWAL, Trisha; US
ALEMOZAFAR, Ali; US
Priority Data:
62/363,13115.07.2016US
Title (EN) COMPOSITIONS AND METHODS FOR FLAVIVIRUS VACCINATION
(FR) COMPOSITIONS ET PROCÉDÉS POUR VACCINATION CONTRE LE FLAVIVIRUS
Abstract:
(EN) Compositions of a recombinant adenovirus based vector vaccine containing one or more flavivirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate immune responses against flaviviruses are also described. Compositions described herein allow for vaccinations in subjects with preexisting immunity to adenovirus.
(FR) L'invention concerne des compositions d'un vaccin à vecteur à base d'adénovirus recombinant contenant un ou plusieurs gène(s) antigénique(s) de flavivirus. L'invention concerne également des procédés pour la construction et la production de tels vaccins et des procédés d'utilisation de ces vaccins pour induire des réponses immunitaires contre les flavivirus. Les compositions selon la présente invention permettent des vaccinations chez des sujets présentant une immunité anti-adénovirus préexistante.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)