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1. (WO2018013975) HDAC INHIBITORS FOR USE WITH NK CELL BASED THERAPIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/013975    International Application No.:    PCT/US2017/042222
Publication Date: 18.01.2018 International Filing Date: 14.07.2017
IPC:
A61K 35/17 (2015.01), A61K 39/02 (2006.01)
Applicants: VIRACTA THERAPEUTICS, INC. [US/US]; 4747 Executive Drive, Suite 700 San Diego, California 92121 (US).
NANTKWEST, INC. [US/US]; 9920 Jefferson Blvd. Culver City, California 90232 (US)
Inventors: WOODY, James N.; (US).
SOON-SHIONG, Patrick; (US)
Agent: HARDT, Ingo; (US).
WHEELER, Matthew; (US)
Priority Data:
62/362,959 15.07.2016 US
Title (EN) HDAC INHIBITORS FOR USE WITH NK CELL BASED THERAPIES
(FR) INHIBITEURS HDAC DESTINÉS À ÊTRE UTILISÉS AVEC DES THÉRAPIES À BASE DE CELLULES NK.
Abstract: front page image
(EN)Provided are methods and compositions for the treatment of cancer. The methods comprise administering to a subject an HDAC inhibitor and an immunotherapeutic agent. In certain instances the immunotherapeutic is an NK cell or a chimeric antigen receptor NK cell.
(FR)L'invention porte sur une méthode et un composé utilisé dans le traitement du cancer. Cette méthode consiste à administrer un inhibiteur de HDAC et un agent immunothérapeutique à un sujet. Dans certains cas, l'immunothérapie est une cellule NK ou un récepteur chimérique d'antigène de cellule NK.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)