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1. (WO2018013951) TARGETING ADENOSINE A2A RECEPTORS FOR THE TREATMENT OF LEVODOPA-INDUCED DYSKINESIAS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/013951    International Application No.:    PCT/US2017/042178
Publication Date: 18.01.2018 International Filing Date: 14.07.2017
IPC:
A61K 31/198 (2006.01), A61P 25/14 (2006.01), A61P 25/16 (2006.01)
Applicants: NORTHWESTERN UNIVERSITY [US/US]; 633 Clark Street Evanston, Illinois 60208 (US)
Inventors: SURMEIER, Dalton James, JR.; (US).
SHEN, Weixing; (US)
Agent: STAPLE, David W.; (US)
Priority Data:
62/362,937 15.07.2016 US
Title (EN) TARGETING ADENOSINE A2A RECEPTORS FOR THE TREATMENT OF LEVODOPA-INDUCED DYSKINESIAS
(FR) CIBLAGE DES RÉCEPTEURS A2A DE L'ADÉNOSINE POUR LE TRAITEMENT DE DYSKINÉSIES INDUITES PAR LA LÉVODOPA
Abstract: front page image
(EN)Provided herein are compositions and methods for the treatment and of neurodegenerative disorders and levodopa-induced dyskinesias. In particular, A2a receptor antagonists are provided, as well as methods for the use of A2a receptor antagonists in the treatment of neurodegenerative disorders (e.g., Parkinsons disease) and the treatment and/or prevention levodopa-induced dyskinesias associated with such treatment.
(FR)La présente invention concerne des compositions et méthodes pour le traitement d'affections neurodégénératives et de dyskinésies induites par la lévodopa. En particulier, l'invention concerne des antagonistes du récepteur A2a, ainsi que des méthodes d'utilisation des antagonistes du récepteur A2a dans le traitement de troubles neurodégénératifs (par exemple la maladie de Parkinson) et dans le traitement et/ou la prévention des dyskinésies induites par la lévodopa associées à un tel traitement.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)