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1. (WO2018013855) IL-15/IL-15 RECEPTOR ALPHA TREATMENT REGIMENS AND USE WITH THERAPEUTIC VACCINES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/013855 International Application No.: PCT/US2017/042002
Publication Date: 18.01.2018 International Filing Date: 13.07.2017
IPC:
A61K 38/20 (2006.01) ,G01N 33/50 (2006.01) ,G01N 33/68 (2006.01) ,A61K 45/06 (2006.01) ,A61P 31/18 (2006.01) ,A61P 37/04 (2006.01) ,A61P 35/00 (2006.01) ,A61K 9/00 (2006.01) ,A61K 39/00 (2006.01)
Applicants: THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES[US/US]; Office of Technology Transfer 6011 Executive Blvd., Suite 325 Rockville, Maryland 20852, US
Inventors: FELBER, Barbara K.; US
PAVLAKIS, George N.; US
VALENTIN, Antonio; US
Agent: LOCKYER, Jean M.; US
BASTIAN, Kevin L.; US
GAO, Chuan; US
GRAHAM, Jamie L.; US
Priority Data:
62/362,22314.07.2016US
Title (EN) IL-15/IL-15 RECEPTOR ALPHA TREATMENT REGIMENS AND USE WITH THERAPEUTIC VACCINES
(FR) SCHÉMAS DE TRAITEMENT AVEC LE RÉCEPTEUR ALPHA DE IL -15/IL -15 ET LEUR UTILISATION AVEC DES VACCINS THÉRAPEUTIQUES
Abstract: front page image
(EN) The invention provides dose escalation regimens for administering IL-15/IL-15Ra in a Fibonacci series to a patient suffering from lymphocytopenia, cancer, or an infectious disease. The inventionfurther provides methods for monitoring treatment of a patient with IL-15.
(FR) L'invention concerne des méthodes et des schémas d'augmentation échelonnée des doses pour administrer de l'IL -15 à un patient en ayant besoin.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)