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1. (WO2018013782) METHOD FOR AROMATIC FLUORINATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/013782    International Application No.:    PCT/US2017/041889
Publication Date: 18.01.2018 International Filing Date: 13.07.2017
IPC:
C07D 213/79 (2006.01), C07D 215/18 (2006.01), C07C 45/61 (2006.01), C07C 45/63 (2006.01), C07C 49/784 (2006.01)
Applicants: DOW GLOBAL TECHNOLOGIES LLC [US/US]; 2040 Dow Center Midland, MI 48674 (US).
THE REGENTS OF THE UNIVERSITY OF MICHIGAN [US/US]; 1600 Huron Parkway Ann Arbor, MI 48109-2590 (US)
Inventors: SANFORD, Melanie, S.; (US).
CISMESIA, Megan, A.; (US).
HANLY, Patrick, S.; (US).
BLAND, Douglas; (US)
Agent: SARUSSI, Steven, J.; (US)
Priority Data:
62/362,725 15.07.2016 US
Title (EN) METHOD FOR AROMATIC FLUORINATION
(FR) PROCÉDÉ POUR FLUORATION AROMATIQUE
Abstract: front page image
(EN)Disclosed is a f fluorination method comprising providing a fluorinating reagent and a solvent to a reaction mixture; providing a compound having the formula Ar-X to the reaction mixture; wherein, A is a aryl, substituted aryl, heteroaryl or substituted heteroaryl, and X is CI, Br, I or NO2, providing tetramethylammonium 2,6-dimethylphenolate to the reaction mixture; and reacting under conditions sufficient to provide a species having the formula Ar-F.
(FR)L'invention concerne un procédé de fluoration f consistant à fournir un réactif de fluoration et un solvant à un mélange de réaction; à fournir un composé ayant la formule Ar-X au mélange de réaction; dans laquelle A représente un aryle, un aryle substitué, un hétéroaryle ou un hétéroaryle substitué, et X représente CI, Br, I ou NO 2 , à fournir du tétraméthylammonium 2,6-diméthylphénolate au mélange de réaction; et à faire réagir sous des conditions suffisantes pour obtenir une espèce de formule Ar-f
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)