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1. (WO2018013711) ENCOCHLEATED ANTIFUNGAL COMPOUNDS FOR CENTRAL NERVOUS SYSTEM DELIVERY AND TREATMENT OF CRYPTOCOCCUS INFECTIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/013711 International Application No.: PCT/US2017/041750
Publication Date: 18.01.2018 International Filing Date: 12.07.2017
IPC:
A61K 9/127 (2006.01) ,A61K 31/7048 (2006.01) ,A61K 31/00 (2006.01)
Applicants: MATINAS BIOPHARMA NANOTECHNOLOGIES, INC.[US/US]; 1545 Route 206 South Suite 302 Bedminster, NJ 07921, US
Inventors: MANNINO, Raphael, J.; US
LU, Ruying; US
KLING, Doug, F.; US
Agent: DONALDSON, Timothy, B.; US
Priority Data:
62/361,35112.07.2016US
62/513,80001.06.2017US
Title (EN) ENCOCHLEATED ANTIFUNGAL COMPOUNDS FOR CENTRAL NERVOUS SYSTEM DELIVERY AND TREATMENT OF CRYPTOCOCCUS INFECTIONS
(FR) COMPOSÉS ANTIFONGIQUES ENCAPSULÉS DANS DES COCHLÉATES POUR ADMINISTRATION AU SYSTÈME NERVEUX CENTRAL ET TRAITEMENT DES INFECTIONS PAR CRYPTOCOCCUS
Abstract:
(EN) The present application is directed to a cochleate composition including one or more cochleates and at least two antifungal compounds selected from amphotericin B, 5 -flucytosine, fluconazole, ketoconazole, ravuconazole, albaconazole, itraconazole, posaconazole, isavuconazole and/or voriconazole. Methods of using the antifungal cochleate formulations are also disclosed.
(FR) L'invention concerne une composition de cochléates comprenant au moins un cochléate et au moins deux composés antifongiques sélectionnés parmi l'amphotéricine B, la 5-flucytosine, le fluconazole, le kétoconazole, le ravuconazole, l'albaconazole, l'itraconazole, le posaconazole, l'isavuconazole et/ou le voriconazole. L'invention concerne égalememt des méthodes d’utilisation de ces préparations de cochléates antifongiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)