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1. (WO2018013534) METHODS FOR TREATING PTEN DEFICIENT EPITHELIAL CANCERS USING A COMBINATION OF ANTI-PI3KBETA AND ANTI-IMMUNE CHECKPOINT AGENTS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/013534    International Application No.:    PCT/US2017/041490
Publication Date: 18.01.2018 International Filing Date: 11.07.2017
IPC:
A61K 31/5377 (2006.01), A61K 45/06 (2006.01), C07D 471/02 (2006.01), C12Q 1/68 (2006.01)
Applicants: DANA-FARBER CANCER INSTITUTE, INC. [US/US]; 450 Brookline Avenue Boston, MA 02215-5450 (US)
Inventors: ZHAO, Jean; (US).
BERGHOLZ, Johann; (US).
FREEMAN, Gordon, J.; (US).
ROBERTS, Thomas, M.; (US)
Agent: SMITH, DeAnn, F.; (US).
BLOUNT, Jennifer; (US).
ABELLEIRA, Susan, M.; (US).
AKHIEZER, Alexander; (US).
CHOI, Philip, S.; (US)
Priority Data:
62/360,596 11.07.2016 US
Title (EN) METHODS FOR TREATING PTEN DEFICIENT EPITHELIAL CANCERS USING A COMBINATION OF ANTI-PI3KBETA AND ANTI-IMMUNE CHECKPOINT AGENTS
(FR) MÉTHODES DE TRAITEMENT DE CANCERS ÉPITHÉLIAUX DÉFICIENTS EN PTEN AU MOYEN D'UNE COMBINAISON D'AGENTS ANTI-PI3KBÊTA ET ANTI-POINT DE CONTRÔLE IMMUNITAIRE
Abstract: front page image
(EN)The present invention relates to methods for treating PTEN deficient epithelial cancers using a combination of anti-PI3Kbeta and anti-immune checkpoint agents.
(FR)La présente invention concerne des méthodes de traitement de cancers épithéliaux déficients en PTEN au moyen d'une combinaison d'agents anti-PI3K kbêta et anti-point de contrôle immunitaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)