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1. (WO2018013483) KV1.3 CHANNEL BLOCKING PEPTIDES AND USES THEREOF

Pub. No.:    WO/2018/013483    International Application No.:    PCT/US2017/041376
Publication Date: Fri Jan 19 00:59:59 CET 2018 International Filing Date: Tue Jul 11 01:59:59 CEST 2017
IPC: A61K 39/395
A61K 47/65
A61P 37/02
A61P 37/06
C07K 14/435
Applicants: THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH
Inventors: WANG, Feng
FANG, Changming
WANG, Rongsheng E.
WANG, Ying
SCHULTZ, Peter G.
Title: KV1.3 CHANNEL BLOCKING PEPTIDES AND USES THEREOF
Abstract:
Disclosed herein are Kv1.3 channel inhibitor peptides and compositions comprising a peptide Kv1.3 inhibitor connected to an antibody sequence. These molecules may be useful for the treatment of T-cell mediated diseases and conditions such as autoimmune diseases.