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1. (WO2018012936) PHARMACEUTICAL COMPOSITION COMPRISING NANOPERFORATOR FOR PREVENTING OR TREATING VIRAL INFECTIOUS DISEASES

Pub. No.:    WO/2018/012936    International Application No.:    PCT/KR2017/007602
Publication Date: Fri Jan 19 00:59:59 CET 2018 International Filing Date: Sat Jul 15 01:59:59 CEST 2017
IPC: A61K 9/127
A61K 38/17
A61K 39/12
G01N 33/569
G01N 33/566
Applicants: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
성균관대학교 산학협력단
YONSEI UNIVERSITY, UNIVERSITY - INDUSTRY FOUNDATION (UIF)
연세대학교 산학협력단
Inventors: KWEON, Dae-Hyuk
권대혁
KONG, Byoungjae
공병재
CHUNG, Woo-Jae
정우재
SEONG, Baik Lin
성백린
LEE, Sukchan
이석찬
Title: PHARMACEUTICAL COMPOSITION COMPRISING NANOPERFORATOR FOR PREVENTING OR TREATING VIRAL INFECTIOUS DISEASES
Abstract:
The present invention relates to a nanoperforator comprising a lipid-bilayer nanodisc and a membrane-structured protein surrounding the nanodisc and to a pharmaceutical composition comprising the nanoperforator as an active ingredient for preventing or treating viral infectious diseases. The use of the lipid-bilayer nanoperforator provided in the present invention can lead to the safe prevention or treatment of a disease caused by viral infection regardless of whether the virus is a variant or not, and thus the present invention can be widely used for the safe and effective treatment of viral infectious diseases.