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1. (WO2018011681) NOVEL PYRIMIDINE CARBOXAMIDES AS INHIBITORS OF VANIN-1 ENZYME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/011681    International Application No.:    PCT/IB2017/054104
Publication Date: 18.01.2018 International Filing Date: 07.07.2017
IPC:
C07D 403/14 (2006.01), C07D 401/14 (2006.01), C07D 413/14 (2006.01), C07D 471/08 (2006.01), C07D 487/04 (2006.01), C07D 487/10 (2006.01), C07D 491/107 (2006.01), C07D 498/10 (2006.01), C07D 498/18 (2006.01), A61K 31/506 (2006.01), A61P 29/00 (2006.01)
Applicants: PFIZER INC. [US/US]; 235 East 42nd Street New York, New York 10017 (US)
Inventors: CASIMIRO-GARCIA, Agustin; (US).
STROHBACH, Joseph Walter; (US).
HEPWORTH, David; (US).
LOVERING, Frank Eldridge; (US).
CHOI, Chulho; (US).
ALLAIS, Christophe Philippe; (US).
WRIGHT, Stephen Wayne; (US)
Agent: WALDRON, Roy F.; (US)
Priority Data:
62/362,098 14.07.2016 US
Title (EN) NOVEL PYRIMIDINE CARBOXAMIDES AS INHIBITORS OF VANIN-1 ENZYME
(FR) NOUVEAUX PYRIMIDINE CARBOXAMIDES UTILISÉES COMME INHIBITEURS DE L'ENZYME VANIN-1
Abstract: front page image
(EN)Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
(FR)L'invention concerne des composés et leurs sels pharmaceutiquement acceptables, les composés présentes la structure représentée par la Formule (I) telle que définie dans la description. L'invention concerne également des compositions pharmaceutiques, des méthodes de traitement, des procédés de synthèse et des intermédiaires correspondants.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)