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1. (WO2018011628) THERAPEUTIC INHIBITORY COMPOUNDS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/011628    International Application No.:    PCT/IB2017/000984
Publication Date: 18.01.2018 International Filing Date: 11.07.2017
IPC:
A61K 31/4196 (2006.01), A61K 31/541 (2006.01), A61K 31/4439 (2006.01)
Applicants: LIFESCI PHARMACEUTICALS, INC. [BB/BB]; Whitepark House, White Park Road Bridgetown, St. Michael, 11135 (BB)
Inventors: MCDONALD, Andrew; (US).
QIAN, Shawn; (US)
Priority Data:
62/360,902 11.07.2016 US
Title (EN) THERAPEUTIC INHIBITORY COMPOUNDS
(FR) COMPOSÉS INHIBITEURS THÉRAPEUTIQUES
Abstract: front page image
(EN)Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting plasma kallikrein. Furthermore, the subject compounds and compositions are useful for the treatment of diseases wherein the inhibition of plasma kallikrein inhibition has been implicated, such as angioedema and the like.
(FR)La présente invention concerne des composés de dérivés hétérocycliques et des compositions pharmaceutiques comprenant ces composés qui sont utiles pour inhiber la kallicréine plasmatique. En outre, les composés et les compositions de l'invention sont utiles pour le traitement de maladies dans lesquelles l'inhibition de l'inhibition de la kallicréine plasmatique a été impliquée, telles que l'œdème de Quincke et analogue.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)