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1. (WO2018010789) NOVEL ANTIBODIES SPECIFICALLY BINDING TO ZIKA VIRUS EPITOPES AND USES THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/010789    International Application No.:    PCT/EP2016/066684
Publication Date: 18.01.2018 International Filing Date: 13.07.2016
IPC:
C07K 16/10 (2006.01), A61P 31/12 (2006.01), A61K 39/395 (2006.01), A61K 39/00 (2006.01)
Applicants: HUMABS BIOMED SA [CH/CH]; Via Mirasole 1 6500 Bellinzona (CH)
Inventors: CORTI, Davide; (CH)
Agent: VON STOSCH, Andreas; (DE)
Priority Data:
Title (EN) NOVEL ANTIBODIES SPECIFICALLY BINDING TO ZIKA VIRUS EPITOPES AND USES THEREOF
(FR) NOUVEAUX ANTICORPS SE LIANT SPÉCIFIQUEMENT AUX ÉPITOPES DU VIRUS ZIKA ET LEURS UTILISATIONS
Abstract: front page image
(EN)The invention relates to antibodies, and antigen binding fragments thereof, that potently neutralize infection of ZIKV. The invention also relates to antigenic sites to which the antibodies and antigen binding fragments bind, as well as to nucleic acids that encode and immortalized B cells that produce such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies and antibody fragments of the invention in screening methods as well as in the diagnosis, prophylaxis and treatment of ZIKV infection.
(FR)L'invention concerne des anticorps et leurs fragments de liaison de l'antigène, qui neutralisent potentiellement les infections par le virus ZIKA. La présente invention concerne également des sites antigéniques auxquels se lient les anticorps et les fragments liant l'antigène, ainsi que des acides nucléiques codant et immortalisant les cellules B qui produisent lesdits anticorps et fragments d'anticorps. En outre, l'invention concerne l'utilisation des anticorps et fragments d'anticorps de l'invention dans des procédés de criblage ainsi que dans le diagnostic, la prophylaxie et le traitement des infections par le virus ZIKA.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)