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1. (WO2018010659) IRREVERSIBLE ELECTROPORATION DEVICE AND OPERATION METHOD THEREFOR

Pub. No.:    WO/2018/010659    International Application No.:    PCT/CN2017/092591
Publication Date: Fri Jan 19 00:59:59 CET 2018 International Filing Date: Thu Jul 13 01:59:59 CEST 2017
IPC: A61B 18/12
A61B 18/14
Applicants: REMEDICINE CO., LTD
上海睿刀医疗科技有限公司
Inventors: WANG, Haifeng
王海峰
Title: IRREVERSIBLE ELECTROPORATION DEVICE AND OPERATION METHOD THEREFOR
Abstract:
An irreversible electroporation device (1, 2). The irreversible electroporation device (1, 2) comprises a pulse forming device (10) configured to generate bipolar pulses, and comprises an electrode (20) configured to receive the bipolar pulses from the pulse forming device (10) and apply the bipolar pulses to a biological tissue. The pulse width of the bipolar pulses and an electric field intensity generated in the biological tissue are set to be sufficient to cause irreversible electroporation on cell membranes of the biological tissue. The bipolar pulses can effectively improve the uniformity of an ablation electric field; and the pulse width of the bipolar pulses and the electric field intensity generated in the biological tissue are sufficient to cause the irreversible electroporation, thereby reducing an ablation blind region.