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1. (WO2018010140) TYPE I INTERFERON RECEPTOR ANTIBODY AND USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/010140 International Application No.: PCT/CN2016/090018
Publication Date: 18.01.2018 International Filing Date: 14.07.2016
IPC:
C07K 16/28 (2006.01) ,A61K 39/395 (2006.01) ,A61P 37/02 (2006.01) ,C12N 15/13 (2006.01)
Applicants: INSTITUTE OF BIOPHYSICS, CHINESE ACADEMY OF SCIENCES[CN/CN]; No.15, Datun Road, Chaoyang District Beijing 100101, CN
Inventors: ZHANG, Liguo; CN
SU, Lishan; CN
LI, Jingyun; CN
MA, Jianping; CN
Agent: JEEKAI&PARTNERS; Floor 15A, Building No.5, 9 Guang'an Road, Fengtai District Beijing 100055, CN
Priority Data:
Title (EN) TYPE I INTERFERON RECEPTOR ANTIBODY AND USE THEREOF
(FR) ANTICORPS DU RÉCEPTEUR DE L'INTERFÉRON DE TYPE I ET SON UTILISATION
(ZH) I型干扰素受体抗体及其用途
Abstract:
(EN) Disclosed are a monoclonal antibody that binds to a type I interferon receptor, and a use thereof. The antibody can inhibit the biological activity of type I interferons, and can be used for treating, preventing, or diagnosing the diseases mediated by the type I interferons. Also provided are an immunoconjugate, a bispecific molecule, and a pharmaceutical composition comprising the antibody.
(FR) L'invention concerne un anticorps monoclonal qui se lie à un récepteur de l'interféron de type I, et son utilisation. L'anticorps peut inhiber l'activité biologique des interférons de type I, et peut être utilisé pour traiter, prévenir ou diagnostiquer les maladies induites par les interférons de type I. L'invention concerne également un immunoconjugué, une molécule bispécifique et une composition pharmaceutique comprenant l'anticorps.
(ZH) 本发明公开了结合I型干扰素受体的单克隆抗体及其用途,所述抗体能够抑制I型干扰素的生物活性,可用于治疗、预防或诊断I型干扰素介导的疾病。还提供了包含所述抗体的免疫偶联物、双特异性分子和药物组合物。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)