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1. (WO2018009822) MODIFIED NUCLEIC ACIDS, HYBRID GUIDE RNAS, AND USES THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/009822    International Application No.:    PCT/US2017/041133
Publication Date: 11.01.2018 International Filing Date: 07.07.2017
IPC:
C12N 9/22 (2006.01), C12N 15/11 (2006.01), C12N 15/90 (2006.01)
Applicants: OHIO STATE INNOVATION FOUNDATION [US/US]; 1524 North High Street Columbus, Ohio 43201 (US)
Inventors: DONG, Yizhou; (US).
LI, Bin; (US)
Agent: PRATHER, Donald M.; (US).
HALL, Miles E.; (US).
MEUNIER, Andrew T.; (US).
CARLIN, Gregory J.; (US).
CURFMAN, Christopher L.; (US)
Priority Data:
62/359,880 08.07.2016 US
62/480,716 03.04.2017 US
Title (EN) MODIFIED NUCLEIC ACIDS, HYBRID GUIDE RNAS, AND USES THEREOF
(FR) ACIDES NUCLÉIQUES MODIFIÉS, ARN-GUIDES HYBRIDES ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present disclosure generally relates to genome editing systems and methods and compounds and compositions for use in Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) genome editing systems. Disclosed herein are modified nucleic acids that modulate the activity of genome editing.
(FR)La présente invention concerne d'une manière générale des systèmes d’édition du génome, des méthodes, des composés et des compositions à utiliser dans des systèmes d'édition du génome à répétitions palindromiques groupées, courtes et espacées régulièrement (CRISPR). Des acides nucléiques modifiés qui modulent l'activité d'édition du génome sont également divulgués.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)