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1. (WO2018009553) AAV2-MEDIATED GENE DELIVERY OF SFASL AS A NEUROPROTECTIVE THERAPY IN GLAUCOMA
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/009553 International Application No.: PCT/US2017/040735
Publication Date: 11.01.2018 International Filing Date: 05.07.2017
IPC:
A61K 48/00 (2006.01) ,C07K 14/005 (2006.01) ,C12N 7/00 (2006.01) ,C12N 15/86 (2006.01)
Applicants: UNIVERSITY OF MASSACHUSETTS[US/US]; 225 Franklin Street Boaton, MA 02110, US
MASSACHUSETTS EYE AND EAR INFIRMARY[US/US]; 243 Cherles Street Boston, MA 02114, US
Inventors: MARSHAK-ROTHSTEIN, Ann; US
GREGORY-KSANDER, Meredith; US
KSANDER, Bruce; US
Agent: YOUNG, Daniel, W.; US
Priority Data:
62/358,54105.07.2016US
62/511,62926.05.2017US
Title (EN) AAV2-MEDIATED GENE DELIVERY OF SFASL AS A NEUROPROTECTIVE THERAPY IN GLAUCOMA
(FR) ADMINISTRATION DE GÈNE À MÉDIATION PAR AAV2 DE SFASL COMME THÉRAPIE NEUROPROTECTRICE DANS LE GLAUCOME
Abstract: front page image
(EN) Methods for treating glaucoma and/or Fas ligand-dependent inflammatory conditions in a subject using soluble Fas ligand (sFasL) or a fragment thereof, which may be rAAV- mediated delivery of sFasL or a fragment thereof to a subject.
(FR) Méthodes de traitement du glaucome et/ou d'états inflammatoires dépendant du ligand de Fas chez un sujet à l'aide du ligand de Fas soluble (sFasL) ou d'un fragment de celui-ci, qui peuvent être une administration médiée par rAAV de sFasL ou d'un fragment de celui-ci à un sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)