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1. (WO2018009505) 1,3-DIHYDROXY-PHENYL DERIVATIVES USEFUL AS IMMUNOMODULATORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/009505    International Application No.:    PCT/US2017/040663
Publication Date: 11.01.2018 International Filing Date: 05.07.2017
IPC:
C07D 401/14 (2006.01), C07D 413/14 (2006.01), C07D 401/12 (2006.01), C07D 405/12 (2006.01), C07D 413/12 (2006.01), C07D 417/12 (2006.01), A61K 31/4427 (2006.01), A61P 37/02 (2006.01)
Applicants: BRISTOL-MYERS SQUIBB COMPANY [US/US]; Route 206 and Province Line Road Princeton, New Jersey 08543 (US)
Inventors: YEUNG, Kap-Sun; (US).
GRANT-YOUNG, Katharine A.; (US).
ZHU, Juliang; (US).
SAULNIER, Mark G.; (US).
FRENNESSON, David B.; (US).
MENG, Zhaoxing; (US).
SCOLA, Paul Michael; (US)
Agent: MINGO, Pamela A.; (US).
BELLOMY, Gregory R.; (US).
CHAO, Yuan; (US).
CLAUSS, Isabelle M.; (US).
DELAUNEY, Ashton J.; (US).
EPPERSON, James; (US).
FARQUHARSON-TORRES, Serena; (US).
GOLIAN, Paul D.; (US).
GREENBLATT, Gary D.; (US).
GUO, Z. Angela; (US).
HADAD, Henry; (US).
HAI, Bing; (US).
JACOBSEN, Barry H.; (US).
KORSEN, Elliott; (US).
LIU, Hong; (US).
LU, Yong; (US).
PARLET, Nickki L.; (US).
SUN, Jing G.; (US).
VANATTEN, Mary K.; (US).
VOM WEGE, Julia; (US).
WALSH, Brian J.; (US)
Priority Data:
62/359,971 08.07.2016 US
Title (EN) 1,3-DIHYDROXY-PHENYL DERIVATIVES USEFUL AS IMMUNOMODULATORS
(FR) DÉRIVÉS DE 1,3-DIHYDROXY-PHÉNYLE UTILES COMME IMMUNOMODULATEURS
Abstract: front page image
(EN)The present disclosure generally relates to compounds of formula (I), wherin R2 is a phenyl or pyridinyl moiety, useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.
(FR)La présente invention concerne de manière générale des composés de formule (I), dans laquelle R2 est un phényle ou moitié pyridinyle, utiles en tant qu'immunomodulateurs. Cette invention concerne des composés, des compositions comprenant ces composés, et leurs méthodes d'utilisation. L'invention concerne en outre des compositions pharmaceutiques comprenant au moins un composé selon l'invention, qui sont utiles pour le traitement de diverses maladies, y compris le cancer et des maladies infectieuses.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)