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1. (WO2018009334) COMPOSITIONS COMPRISING RUMENIC ACID-RICH CONJUGATED LINOLEIC ACID FOR JOINT HEALTH
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2018/009334 International Application No.: PCT/US2017/038286
Publication Date: 11.01.2018 International Filing Date: 20.06.2017
IPC:
A61K 31/201 (2006.01) ,A61K 31/231 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
201
having one or two double bonds, e.g. oleic or linoleic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
23
of acids having a carboxyl group bound to a chain of seven or more carbon atoms
231
having one or two double bonds
Applicants:
STEPAN SPECIALTY PRODUCTS, LLC [US/US]; 1209 Orange Street Wilmington, DE 19801, US
Inventors:
HEYDINGER GALANTE, Jenifer; US
KEIZER, Hiskias, Gerrit; NL
Agent:
SCHUCHARDT, Jonathan, L.; US
Priority Data:
62/359,71808.07.2016US
Title (EN) COMPOSITIONS COMPRISING RUMENIC ACID-RICH CONJUGATED LINOLEIC ACID FOR JOINT HEALTH
(FR) COMPOSITIONS COMPRENANT DE L'ACIDE LINOLÉIQUE CONJUGUÉ RICHE EN ACIDE RUMENIQUE POUR LA SANTÉ DES ARTICULATIONS
Abstract:
(EN) Methods for enhancing joint function and for treating or preventing age-related joint discomfort in an adult human are disclosed. The methods comprise administering to the human a dietetic food, medical food, or food supplement. The food or food supplement comprises a rumenic acid-rich conjugated linoleic acid (RAR-CLA), or a pharmaceutically acceptable salt, ester, mono-, di-, or triglyceride, metabolic precursor thereof, or mixture thereof, in an amount effective to enhance joint function or to alleviate joint discomfort in the human. The RAR-CLA comprises c/s-9, frans-1 1 linoleic acid and frans-10, c/s-12 linoleic acid isomers in a weight ratio of at least 2: 1. Enrichment of a dietetic food, medical food, or food supplement with RAR-CLA can help to improve joint function and/or alleviate joint discomfort. Longer-term studies should help to further elucidate the potential impact of RAR-CLA supplementation on joint function in older adults.
(FR) L'invention porte également sur des procédés pour améliorer la fonction articulaire et pour traiter ou prévenir une gêne liée à l'âge chez un être humain adulte. Ces méthodes consistent à administrer à l'être humain un aliment diététique, un aliment médical ou un supplément alimentaire. L'aliment ou supplément alimentaire comprend un acide linoléique conjugué riche en acide rumenique (RAR-CLA), ou un sel pharmaceutiquement acceptable, un ester, un mono -, di-ou triglycéride, un précurseur métabolique de celui-ci, ou un mélange de ceux-ci, en quantité efficace pour améliorer la fonction articulaire ou pour soulager une gêne articulaire chez l'être humain. Le RAR-CLA comprend des isomères c/s -9, frans-11 linoléique et frans-10, des isomères d'acide linoléique c/s -12 dans un rapport pondéral d'au moins 2 : 1 L'enrichissement d'un aliment diététique, d'un aliment médical ou d'un supplément alimentaire avec le RAR-CLA peut aider à améliorer la fonction articulaire et/ou à soulager une gêne articulaire. Des études à long terme doivent aider à élucider davantage l'impact potentiel d'une supplémentation de RAR-CLA sur la fonction articulaire chez des adultes plus âgés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3481388