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|1. (WO2018007956) IMMEDIATE RELEASE PHARMACEUTICAL COMPOSITION OF IRON CHELATING AGENTS|
|Applicants:||JUBILANT GENERICS LIMITED
NAKHAT, Premchand Dalichandji
GAT, Ganesh Vinayak
MEHTA, Kamal S
|Title:||IMMEDIATE RELEASE PHARMACEUTICAL COMPOSITION OF IRON CHELATING AGENTS|
of the invention The present invention relates to a stable, immediate release solid oral pharmaceutical compositions comprising iron chelating agents like Deferasirox and at least one pharmaceutical acceptable excipient wherein the composition is free of glidant. Prior art discloses various technical challenges and suggest restrictive and complex solutions for the development of immediate release dosage forms of Deferasirox such as utilizing a large number of excipients or non-conventional formulation techniques. The glidant free immediate release solid oral pharmaceutical composition of Deferasirox, prepared as per present invention exhibited desirable technical attributes like pharmaceutical stability, flow properties and comparable dissolution, bioequivalence against reference listed drug.