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1. (WO2018007922) ANTI-TRANSTHYRETIN ANTIBODIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/007922 International Application No.: PCT/IB2017/053984
Publication Date: 11.01.2018 International Filing Date: 30.06.2017
IPC:
C07K 16/18 (2006.01) ,A61K 39/00 (2006.01)
Applicants: PROTHENA BIOSCIENCES LIMITED[IE/IE]; Adelphi Plaza, Upper George's Street Dun Laoghaire Co. Dublin A96 T927, IE
UNIVERSITY HEALTH NETWORK[CA/CA]; 190 Elizabeth Street R. Fraser Elliott Building, Room 1S-417 Toronto, Ontario M5G 2C4, CA
Inventors: LIU, Yue; US
NIJJAR, Tarlochan S.; US
CHAKRABARTTY, Avijit; CA
HIGAKI, Jeffrey N; US
Priority Data:
15/201,42302.07.2016US
Title (EN) ANTI-TRANSTHYRETIN ANTIBODIES
(FR) ANTICORPS ANTI-TRANSTHYRÉTINE
Abstract: front page image
(EN) The invention provides antibodies that specifically bind transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for diagnosing TTR amyloidosis and inhibiting or reducing aggregation of TTR, among other applications.
(FR) L'invention concerne des anticorps qui se lient spécifiquement à la transthyrétine (TTR). Les anticorps peuvent être utilisés pour traiter ou effectuer une prophylaxie de maladies ou de troubles associés à l'accumulation de TTR ou à l'accumulation de dépôts de TTR (par exemple, amyloïdose de TTR). Les anticorps peuvent également être utilisés pour diagnostiquer l'amylose de TTR et inhiber ou réduire l'agrégation de TTR, entre autres applications.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)