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1. (WO2018007554) VINFLUNINE AND PD1 AND/OR PDL1 INHIBITOR AS PHARMACEUTICAL COMBINATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/007554    International Application No.:    PCT/EP2017/067012
Publication Date: 11.01.2018 International Filing Date: 06.07.2017
IPC:
A61K 39/395 (2006.01), A61K 45/06 (2006.01), A61K 31/475 (2006.01), A61P 35/00 (2006.01)
Applicants: PIERRE FABRE MEDICAMENT [FR/FR]; 45, place Abel Gance 92100 BOULOGNE-BILLANCOURT (FR)
Inventors: KRUCZYNSKI, Anna; (FR).
VANDENBERGHE, Isabelle; (FR).
FERRE, Pierre; (FR)
Agent: REGIMBEAU; 20, rue de Chazelles 75847 PARIS CEDEX 17 (FR)
Priority Data:
16305851.4 06.07.2016 EP
Title (EN) VINFLUNINE AND PD1 AND/OR PDL1 INHIBITOR AS PHARMACEUTICAL COMBINATION
(FR) COMBINAISON PHARMACEUTIQUE COMPRENANT LA VINFLUNINE ET L’INHIBITEUR DE PD1 ET/OU DE PDL1
Abstract: front page image
(EN)The present invention relates to a pharmaceutical combination comprising: (a) vinflunine or a pharmaceutically acceptable salt thereof, and (b) at least one PD1 -inhibitor and/or at least one PD-L1 -inhibitor or pharmaceutically acceptable salt thereof. Such a pharmaceutical combination is useful as a drug, notably in the treatment of a proliferative disease, such as cancer.
(FR)La présente invention concerne une combinaison pharmaceutique comprenant : (a) de la vinflunine ou un sel pharmaceutiquement acceptable de celle-ci, et (b) au moins un inhibiteur de PD1 et/ou au moins un inhibiteur de PD-L1 ou un sel pharmaceutiquement acceptable de celui-ci. Cette combinaison pharmaceutique est utile en tant que médicament, notamment dans le traitement d'une maladie proliférative, telle que le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)