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1. (WO2018007198) METHOD FOR PREPARATION OF INTERMEDIATES USEFUL FOR PREPARATION OF THAPSIGARGIN AND NORTRILOBOLIDE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/007198    International Application No.:    PCT/EP2017/065806
Publication Date: 11.01.2018 International Filing Date: 27.06.2017
IPC:
C07C 50/10 (2006.01), C07C 50/32 (2006.01), C07D 307/93 (2006.01)
Applicants: LEO PHARMA A/S [DK/DK]; Industriparken 55 2750 Ballerup (DK)
Inventors: CHU, Hang; (US).
SMITH, Joel M.; (US).
BARAN, Phillipe S.; (US)
Priority Data:
62/358,418 05.07.2016 US
62/397,130 20.09.2016 US
Title (EN) METHOD FOR PREPARATION OF INTERMEDIATES USEFUL FOR PREPARATION OF THAPSIGARGIN AND NORTRILOBOLIDE
(FR) PROCÉDÉ DE PRÉPARATION D'INTERMÉDIAIRES UTILES POUR LA PRÉPARATION DE THAPSIGARGINE ET DE NORTRILOBOLIDE
Abstract: front page image
(EN)The present invention relates to the preparation of Thapsigargin (1) and Nortrilobolide (2). The invention further relates to intermediates and preparation of said intermediates which are useful for the preparation of (1) and (2).
(FR)La présente invention concerne la préparation de Thapsigargine (1) et de Nortrilobolide (2). L'invention concerne en outre des intermédiaires et la préparation desdits intermédiaires qui sont utiles pour la préparation de (1) et (2).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)