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1. (WO2018006801) ORPHAN NUCLEAR RECEPTOR NUR77 LIGAND AND APPLICATION THEREOF 
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Pub. No.: WO/2018/006801 International Application No.: PCT/CN2017/091716
Publication Date: 11.01.2018 International Filing Date: 04.07.2017
IPC:
C07J 63/00 (2006.01) ,A61K 31/56 (2006.01) ,A61K 31/015 (2006.01) ,A61P 3/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
J
STEROIDS
63
Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
01
Hydrocarbons
015
carbocyclic
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
04
Anorexiants; Antiobesity agents
Applicants:
厦门大学 XIAMEN UNIVERSITY [CN/CN]; 中国福建省厦门市 思明区思明南路422号 No.422 Si Ming Nan Road, Siming District Xiamen, Fujian 361005, CN
Inventors:
张晓坤 ZHANG, Xiaokun; CN
林祥志 LIN, Xiangzhi; CN
苏迎 SU, Ying; CN
曾志平 ZENG, Zhiping; CN
胡梦婕 HU, Mengjie; CN
罗强 LUO, Qiang; CN
朱怡 ZHU, Yi; CN
古丽米然阿里同别克 GULIMIRAN, Alitongbieke; CN
Agent:
中国国际贸易促进委员会专利商标事务所 CCPIT PATENT AND TRADEMARK LAW OFFICE; 中国北京市 西城区阜成门外大街2号万通新世界广场8层 8th Floor, Vantone New World Plaza 2 Fuchengmenwai Street, Xicheng District Beijing 100037, CN
Priority Data:
201610520308.804.07.2016CN
Title (EN) ORPHAN NUCLEAR RECEPTOR NUR77 LIGAND AND APPLICATION THEREOF 
(FR) LIGAND DU RÉCEPTEUR NUCLÉAIRE ORPHELIN NUR77 ET SON APPLICATION 
(ZH) 孤儿核受体Nur77的配体及其用途 
Abstract:
(EN) The present application relates to an orphan nuclear receptor Nur77 ligand and an application thereof. The application specifically relates to a compound represented by formula I and application of the compound as the orphan nuclear receptor Nur77 ligand. The application further relates to an application of the compound represented by formula I for preventing or treating a disease related to the orphan nuclear receptor Nur77.
(FR) La présente invention concerne un ligand du récepteur nucléaire orphelin Nur77 et une application de celui-ci. L'invention concerne spécifiquement un composé représenté par la formule I et l'application du composé en tant que ligand du récepteur nucléaire orphelin Nur77. L'invention concerne en outre une application du composé représenté par la formule I pour prévenir ou traiter une maladie liée au récepteur nucléaire orphelin Nur77.
(ZH) 本申请涉及孤儿核受体Nur77的配体及其用途。特别地,本申请涉及如式I所示的化合物用作孤儿核受体Nur77的配体的用途。此外,本申请还涉及如式I所示的化合物用于预防或治疗与孤儿核受体Nur77相关的疾病的用途,
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)