Search International and National Patent Collections

1. (WO2018006092) AMINO ACID COPOLYMER COMPOSITIONS AND USES THEREOF

Pub. No.:    WO/2018/006092    International Application No.:    PCT/US2017/040598
Publication Date: Fri Jan 05 00:59:59 CET 2018 International Filing Date: Tue Jul 04 01:59:59 CEST 2017
IPC: A61K 39/00
A61K 31/74
A61P 37/04
A61P 25/28
Applicants: DECLION HOLDINGS LLC
Inventors: ZANELLI, Eric
Title: AMINO ACID COPOLYMER COMPOSITIONS AND USES THEREOF
Abstract:
The instant disclosure describes compositions comprising mixtures of polypeptides comprising one or more antigenic regions and one or more random copolymer regions. In certain embodiments, the amino acid copolymer compositions of the disclosure are capable of acting as antigen specific therapeutics and are useful as vaccines, such compositions synthesized according to a set of rules regarding the identity and the frequency of occurrence of amino acids at each position along the length of the polypeptides. The resulting compositions are mixtures of related polypeptides for numerous therapeutic, research and diagnostic uses.