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1. (WO2018005881) OXADIAZEPINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEPATITIS B INFECTIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/005881    International Application No.:    PCT/US2017/040130
Publication Date: 04.01.2018 International Filing Date: 29.06.2017
IPC:
C07D 498/04 (2006.01), C07D 487/04 (2006.01), C07D 471/04 (2006.01), A61K 31/553 (2006.01), A61K 31/551 (2006.01), A61P 31/12 (2006.01)
Applicants: NOVIRA THERAPEUTICS, INC. [US/US]; 3805 Old Easton Road Doylestown, PA 18902 (US)
Inventors: KUDUK, Scott; (US).
HARTMAN, George, D.; (US)
Agent: SHIRTZ, Joseph, F.; (US).
DAVIS, Bradley, E.; (US)
Priority Data:
62/511,565 26.05.2017 US
62/356,487 29.06.2016 US
Title (EN) OXADIAZEPINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEPATITIS B INFECTIONS
(FR) DÉRIVÉS D'OXADIAZÉPINONE ET LEUR UTILISATION DANS LE TRAITEMENT D'INFECTIONS PAR L'HÉPATITE B
Abstract: front page image
(EN)Provided herein are compounds of formula (IA) and (III) useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
(FR)L'invention concerne des composés de formule (IA) et (III) utiles pour le traitement d'une infection par VHB chez un sujet en ayant besoin, des compositions pharmaceutiques les contenant, et des méthodes d'inhibition, d'élimination, ou de prévention d'une infection par le VHB chez ledit sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)