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1. (WO2018005640) MATERIALS AND METHODS FOR MODIFYING THE ACTIVITY OF T CELLS

Pub. No.:    WO/2018/005640    International Application No.:    PCT/US2017/039739
Publication Date: Fri Jan 05 00:59:59 CET 2018 International Filing Date: Thu Jun 29 01:59:59 CEST 2017
IPC: C12N 5/0783
C12N 15/113
C12N 15/117
Applicants: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventors: BLAZAR, Bruce R.
HIPPEN, Keli
REDDY, Pavan
SUN, Yaping
GARZON, Ramiro
Title: MATERIALS AND METHODS FOR MODIFYING THE ACTIVITY OF T CELLS
Abstract:
This disclosure provides miRNA/mRNA pairs that can be used to increase the efficacy of T cells or to down-modulate T cell efficacy and restore equilibrium.