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1. (WO2018005493) REGENERATABLE CURLI NANOFIBER-BASED CATALYSTS FOR MULTISTEP BIOTRANSFORMATIONS
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Pub. No.: WO/2018/005493 International Application No.: PCT/US2017/039505
Publication Date: 04.01.2018 International Filing Date: 27.06.2017
IPC:
C07K 14/245 (2006.01) ,C07K 14/24 (2006.01) ,C07K 14/195 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
24
from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
245
Escherichia (G)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
24
from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
Applicants:
PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US/US]; 17 Quincy Street Cambridge, MA 02138, US
Inventors:
JOSHI, Neel, Satish; US
NUSSBAUMER, Martin, G.; US
Agent:
ZACHARAKIS, Maria, Laccotripe; US
BELT, Erik, P.; US
BLAZESKI, George; US
BAI, Mei; US
BOWLES, Anita, M.; US
Priority Data:
62/354,84327.06.2016US
62/506,72216.05.2017US
Title (EN) REGENERATABLE CURLI NANOFIBER-BASED CATALYSTS FOR MULTISTEP BIOTRANSFORMATIONS
(FR) CATALYSEURS À BASE DE NANOFIBRES CURLI POUVANT ÊTRE RÉGÉNÉRÉS DESTINÉS À DES BIOTRANSFORMATIONS EN PLUSIEURS ÉTAPES
Abstract:
(EN) Disclosed herein are engineered bacteria that manufacture biofilms from bacterial amyloid structures known as curli fibers. These biofilms and biofilm matrices are capable of immobilizing enzymes and generating catalytic surfaces.
(FR) L'invention concerne des bactéries modifiées qui produisent des biofilms à partir de structures amyloïdes bactériennes connues sous le nom de fibres curli. Ces biofilms et matrices de biofilms sont capables d'immobiliser des enzymes et de générer des surfaces catalytiques.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)