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1. (WO2018005330) MODIFIED FRAGMENTS FROM THE OCTAREPEAT REGION OF PRION PROTEIN AS HEMIN BINDERS

Pub. No.:    WO/2018/005330    International Application No.:    PCT/US2017/039210
Publication Date: Fri Jan 05 00:59:59 CET 2018 International Filing Date: Tue Jun 27 01:59:59 CEST 2017
IPC: A61K 9/48
A61K 38/04
A61K 38/08
A61K 39/00
Applicants: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Inventors: BIENKIEWICZ, Ewa, Anna
Title: MODIFIED FRAGMENTS FROM THE OCTAREPEAT REGION OF PRION PROTEIN AS HEMIN BINDERS
Abstract:
An example of the composition incudes at least one amino acid sequence from the octarepeat region of hemin that is modified by substituting at least one proline (P) residue in the amino acid sequence. The composition is effective to bind with hemin and for treating hemorrhagic injury