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1. (WO2018005330) MODIFIED FRAGMENTS FROM THE OCTAREPEAT REGION OF PRION PROTEIN AS HEMIN BINDERS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/005330    International Application No.:    PCT/US2017/039210
Publication Date: 04.01.2018 International Filing Date: 26.06.2017
IPC:
A61K 9/48 (2006.01), A61K 38/04 (2006.01), A61K 38/08 (2006.01), A61K 39/00 (2006.01)
Applicants: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. [US/US]; 2010 Levy Avenue Suite 282 Tallahasse, Florida 32310 (US)
Inventors: BIENKIEWICZ, Ewa, Anna; (US)
Agent: RAMSEY, Christopher, M.; (US)
Priority Data:
62/354,957 27.06.2016 US
Title (EN) MODIFIED FRAGMENTS FROM THE OCTAREPEAT REGION OF PRION PROTEIN AS HEMIN BINDERS
(FR) FRAGMENTS MODIFIÉS DE LA RÉGION D’OCTARÉPÉTITION DE LA PROTÉINE DE PRION EN TANT QU’AGENTS DE LIAISON D’HÉMINE
Abstract: front page image
(EN)An example of the composition incudes at least one amino acid sequence from the octarepeat region of hemin that is modified by substituting at least one proline (P) residue in the amino acid sequence. The composition is effective to bind with hemin and for treating hemorrhagic injury
(FR)Un exemple de la composition comprend au moins une séquence d’acides aminés de la région d’octarépétition d’hémine qui est modifiée par substitution d’au moins un résidu de proline (P) dans la séquence d’acides aminés. La composition est efficace pour se lier à l’hémine et pour traiter une lésion hémorragique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)