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1. (WO2018005192) COMPOUNDS AND THEIR USE FOR REDUCING URIC ACID LEVELS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/005192    International Application No.:    PCT/US2017/038522
Publication Date: 04.01.2018 International Filing Date: 21.06.2017
IPC:
C07D 403/12 (2006.01), A61K 31/513 (2006.01), A61K 31/519 (2006.01), A61P 3/00 (2006.01), C07D 239/60 (2006.01), C07D 401/12 (2006.01), C07D 413/12 (2006.01), C07D 417/12 (2006.01), C07D 487/04 (2006.01), C07D 491/113 (2006.01), C07D 491/12 (2006.01), C07D 498/04 (2006.01)
Applicants: ACQUIST LLC; (US)
Inventors: PIWINSKI, John J.; (US).
BUCKLE, Ronald N.; (US).
LARIVÉE, Alexandre; (CA).
SIDDIQUI, Arshad; (CA).
WARRELL, Raymond P., Jr.; (US)
Agent: FUGIT, Donna R.; (US)
Priority Data:
62/356,685 30.06.2016 US
62/358,669 06.07.2016 US
Title (EN) COMPOUNDS AND THEIR USE FOR REDUCING URIC ACID LEVELS
(FR) COMPOSÉS ET LEUR UTILISATION POUR RÉDUIRE LES NIVEAUX D'ACIDE URIQUE
Abstract: front page image
(EN)Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders of uric acid metabolism, and for maintaining normal uric acid levels in blood or serum are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.
(FR)La présente invention concerne des composés bifonctionnels qui augmentent l'excrétion de l'acide urique et réduisent la production de l'acide urique, ainsi que des composés monofonctionnels qui augmentent l'excrétion de l'acide urique ou réduisent la production de l'acide urique. L'invention concerne également des procédés d'utilisation de ces composés pour réduire les niveaux de l'acide urique dans le sang ou le sérum, pour traiter les troubles du métabolisme de l'acide urique, et pour maintenir les niveaux normaux de l'acide urique dans le sang ou le sérum. La présente invention concerne en outre des compositions pharmaceutiques comprenant les composés bifonctionnels et monofonctionnels.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)