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1. (WO2018005145) FLOWABLE HEMOSTATIC GEL COMPOSITION AND ITS METHODS OF USE
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Pub. No.: WO/2018/005145 International Application No.: PCT/US2017/038113
Publication Date: 04.01.2018 International Filing Date: 19.06.2017
IPC:
A61K 38/39 (2006.01) ,A61L 27/22 (2006.01) ,A61L 24/04 (2006.01) ,A61L 27/24 (2006.01) ,A61L 24/10 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
39
Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin (CIG)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
14
Macromolecular materials
22
Polypeptides or derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24
Surgical adhesives or cements; Adhesives for colostomy devices
04
containing macromolecular materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
14
Macromolecular materials
22
Polypeptides or derivatives thereof
24
Collagen
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24
Surgical adhesives or cements; Adhesives for colostomy devices
04
containing macromolecular materials
10
Polypeptides; Proteins
Applicants:
PHILLIPS, Victor Matthew [US/US]; US
Inventors:
PHILLIPS, Victor Matthew; US
GARNER, John; US
Agent:
LONGMEYER, Michael H.; US
RASCHE, Patrick W.; US
AMODIO, Lucas M.; US
ALLEN, Derick E.; US
ATKINS, Bruce T.; US
BEULICK, John S.; US
BLOCK, Zachary J.; US
BRENNAN, Patrick E.; US
BROPHY, Richard L.; US
COYLE, Patrick J.; US
FITZGERALD, Daniel M.; US
FLOREK, Erin M.; US
GOFF, Christopher M.; US
HARPER, James D.; US
HARPER, Jesse S.; US
HEINEN JR., James M.; US
HENSON, James W.; US
HILMERT, Laura J.; US
HOEKEL, Jennifer E.; US
KEPPEL, Nicholas A.; US
MUNSELL, Michael G.; US
MUELLER, Jacob R.; US
POLAND, Eric G.; US
RAYMOND JR., Donald D.; US
REESER III, Robert B.; US
SCHUTH, Richard A.; US
SLATER, Brian T.; US
SNIDER, Josh C.; US
SOOTER, Miranda M.; US
THOMAS, Mark A.; US
VANDER MOLEN, Michael J.; US
VANVLIET, David S.; US
WULLER, Adam R.; US
ZYCHLEWICZ, William J.; US
DINGLEDINE, Grant A.; US
MCCAY, Michael G.; US
MOLLER-JACOBS, Rose L.; US
VANENGELEN, Catherine E.; US
SMELCER, Paul L.; US
ZEE-CHENG, Brendan R.; US
TRUITT, Tracey S.; US
SCHNIEDERS, Kelley A.; US
Priority Data:
15/195,08728.06.2016US
Title (EN) FLOWABLE HEMOSTATIC GEL COMPOSITION AND ITS METHODS OF USE
(FR) COMPOSITION DE GEL HÉMOSTATIQUE FLUIDE ET SES MÉTHODES D'UTILISATION
Abstract:
(EN) A flowable hemostatic gel composition is provided for use at a site of a defect within a biological tissue. The flowable hemostatic gel composition includes a flowable gel solution that includes a biopolymer dissolved in a first solvent. The biopolymer is configured to cross-link with red blood cells at the site to facilitate clot formation at the site. The flowable hemostatic gel composition also includes at least one additional active agent.
(FR) L'invention concerne une composition de gel hémostatique fluide destinée à être utilisée sur le site d'un défaut à l'intérieur d'un tissu biologique. La composition de gel hémostatique fluide comprend une solution de gel fluide qui inclut un biopolymère dissous dans un premier solvant. Le biopolymère est conçu pour se réticuler avec les globules rouges au niveau du site pour faciliter la formation de caillots sur le site. La composition de gel hémostatique fluide comprend également au moins un agent actif supplémentaire.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)