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1. (WO2018004254) BIOMARKER FOR CHECKING EXPOSURE TO PARTICULATE MATTER, AND METHOD FOR CHECKING EXPOSURE TO PARTICULATE MATTER USING SAME
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Pub. No.: WO/2018/004254 International Application No.: PCT/KR2017/006841
Publication Date: 04.01.2018 International Filing Date: 28.06.2017
IPC:
C12Q 1/68 (2018.01) ,G01N 33/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
(주)아모레퍼시픽 AMOREPACIFIC CORPORATION [KR/KR]; 서울시 용산구 한강대로 106 106, Hangang-daero, Yongsan-gu, Seoul 04386, KR
Inventors:
김형준 KIM, Hyoung-June; KR
나혜원 NA, Hye-Won; KR
배일홍 BAE, Il-Hong; KR
정창조 JUNG, Changjo; KR
이태룡 LEE, Tae Ryong; KR
Agent:
김순영 KIM, Sun-young; KR
Priority Data:
10-2016-008170229.06.2016KR
Title (EN) BIOMARKER FOR CHECKING EXPOSURE TO PARTICULATE MATTER, AND METHOD FOR CHECKING EXPOSURE TO PARTICULATE MATTER USING SAME
(FR) BIOMARQUEUR PERMETTANT DE VÉRIFIER L'EXPOSITION À UNE MATIÈRE PARTICULAIRE, ET PROCÉDÉ PERMETTANT DE VÉRIFIER L'EXPOSITION À UNE MATIÈRE PARTICULAIRE UTILISANT CELUI-CI
(KO) 미세먼지 노출 여부 확인용 바이오마커 및 이를 이용하는 확인방법
Abstract:
(EN) The present specification can provide a GSDMA gene as a biomarker capable of objectively checking whether a subject is exposed to particulate matter. Since the GSDMA gene does not react to other external environmental stimulations but specifically shows expression level variations to particulate matter, the GSDMA gene can be used as a particulate matter-specific biomarker.
(FR) La présente invention peut fournir un gène GSDMA utilisé comme biomarqueur permettant de vérifier objectivement si un sujet est exposé à une matière particulaire. Comme le gène GSMA ne réagit pas à d'autres stimulations environnementales externes mais présente plus particulièrement des variations de niveau d'expression à la matière particulaire, le gène GSMA peut être utilisé comme biomarqueur spécifique de la matière particulaire.
(KO) 본 명세서에서는 대상이 미세먼지에 노출되었는지 여부를 객관적으로 확인할 수 있는 바이오마커로서 GSDMA 유전자를 제공할 수 있다. GSDMA 유전자는 기타 외부 환경 자극에는 반응하지 않으면서 미세먼지에 특이적으로 발현량 변화를 나타내어 미세먼지 특이적 바이오마커로서 사용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)