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1. (WO2018004173) COMPOSITION FOR SUPPRESSING ADIPOCYTE DIFFERENTIATION AND METHOD FOR SCREENING SUPPRESSIVE MATERIAL AGAINST ADIPOCYTE DIFFERENTIATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/004173 International Application No.: PCT/KR2017/006451
Publication Date: 04.01.2018 International Filing Date: 20.06.2017
IPC:
A61K 48/00 (2006.01) ,A23L 33/13 (2016.01) ,A61K 8/60 (2006.01) ,A61Q 19/00 (2006.01) ,C12Q 1/68 (2018.01)
Applicants: AMOREPACIFIC CORPORATION[KR/KR]; 106, Hangang-daero, Yongsan-gu, Seoul 04386, KR
Inventors: PARK, Pil Joon; KR
CHO, Si Young; KR
LEE, Tae Ryong; KR
CHO, Eun-Gyung; KR
Agent: KIM, Sun-young; KR
Priority Data:
10-2016-008183129.06.2016KR
10-2017-007236709.06.2017KR
Title (EN) COMPOSITION FOR SUPPRESSING ADIPOCYTE DIFFERENTIATION AND METHOD FOR SCREENING SUPPRESSIVE MATERIAL AGAINST ADIPOCYTE DIFFERENTIATION
(FR) COMPOSITION POUR INHIBER LA DIFFÉRENCIATION DES ADIPOCYTES, ET MÉTHODE DE CRIBLAGE DE SUBSTANCES INHIBITRICES DE LA DIFFÉRENCIATION DES ADIPOCYTES
(KO) 지방 세포 분화 억제용 조성물 및 지방 세포 분화 억제 물질의 스크리닝 방법
Abstract: front page image
(EN) Disclosed in the specification are a composition comprising a suppressive material against SRBC expression or activity as an effective ingredient and a method for screening a suppressive material against adipocyte differentiation. A composition comprising a suppressive material against SRBC expression or activity as an effective ingredient according to an aspect of the present invention suppresses the differentiation of adipocytes and can be thus used for obesity prevention or alleviation. In addition, a method for screening a suppressive material against adipocyte differentiation according to an aspect of the present invention can screen a suppressive material against adipocyte differentiation simply, quickly, and effectively by treating dermal adipocytes with a test material and examining a relative expression level of an SRBC gene.
(FR) L'invention concerne une composition comprenant comme principe actif une substance inhibant l'expression ou l'activité de SRBC, ainsi qu'une méthode de criblage de substances inhibitrices de la différenciation des adipocytes. Selon un aspect de la présente invention, une composition comprenant comme principe actif une substance inhibant l'expression ou l'activité de SRBC inhibe la différenciation des adipocytes et peut donc être utilisée pour prévenir ou atténuer l'obésité. De plus, selon un aspect de la présente invention, une méthode de criblage de substances inhibitrices de la différenciation des adipocytes peut permettre de cribler des substances inhibitrices de la différenciation des adipocytes de façon simple, rapide et efficace en traitant les adipocytes du derme avec une substance à tester et en analysant le niveau relatif de l'expression du gène SRBC.
(KO) 본 명세서에는 SRBC 발현 또는 활성 억제 물질을 유효성분으로 포함하는 조성물 및 지방세포 분화 억제 물질의 스크리닝 방법이 개시된다. 본 발명의 일 측면인 SRBC의 발현 또는 활성 억제 물질을 유효성분으로 포함하는 조성물은 지방세포의 분화를 억제하여, 비만 예방 또는 개선용도로 사용될 수 있다. 또한, 본 발명의 일 측면인 지방세포 분화 억제 물질의 스크리닝 방법은, 피부 지방세포에 시험물질을 처리하고 SRBC 유전자의 상대적 발현 정도를 확인함으로써, 간편하고 신속하며 효율적으로 지방세포 분화 억제 물질을 스크리닝할 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)