Search International and National Patent Collections

1. (WO2018004062) APOPTOSIS REGULATORY GENE DETECTED IN IRRADIATED-THYMIC LYMPHOMA CELL AND METHOD FOR DETECTING SAME

Pub. No.:    WO/2018/004062    International Application No.:    PCT/KR2016/010072
Publication Date: Fri Jan 05 00:59:59 CET 2018 International Filing Date: Fri Sep 09 01:59:59 CEST 2016
IPC: C12Q 1/68
G01N 33/574
Applicants: KOREA HYDRO & NUCLEAR POWER CO., LTD
한국수력원자력 주식회사
Inventors: KIM, Hee Sun
김희선
CHOI, Hoon
최훈
YANG, Kwang Hee
양광희
BAEK, Yun-Mi
백윤미
KEUM, Dong-Kwon
금동권
SHIM, Hee Youn
심희연
HWANG, Byulnim
황별님
Title: APOPTOSIS REGULATORY GENE DETECTED IN IRRADIATED-THYMIC LYMPHOMA CELL AND METHOD FOR DETECTING SAME
Abstract:
The present invention relates to an apoptosis regulatory gene detected in an irradiated-thymic lymphoma cell and, more particularly, to a method for detecting an apoptosis regulatory gene detected in a low-dose-rate and low-level-irradiated thymic lymphoma cell of a mouse. The present invention as described above has an effect of revealing the function of an apoptosis regulatory gene by means of irradiation and providing a gene profile, by detecting an apoptosis regulatory gene detected in an irradiated-thymic lymphoma cell. In addition, an apoptosis regulatory gene detected in an irradiated-thymic lymphoma cell can be used to construct a gene profile that can assess the dose-response relationship of industrial and healthcare workers living in a low-level-radiation environment. An apoptosis regulatory gene detected in an irradiated-thymic lymphoma cell can be used as an index capable of evaluating the extent of cancer progression and the degree of treatment in patients with thymic lymphoma. A method for detecting an apoptosis regulatory gene detected in an irradiated-thymic lymphoma cell can be used for the preparation of a composition for diagnosing thymic lymphoma and a diagnostic kit.