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1. (WO2018003997) PROPHYLACTIC OR THERAPEUTIC AGENT FOR ORGAN FIBROSIS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/003997 International Application No.: PCT/JP2017/024246
Publication Date: 04.01.2018 International Filing Date: 30.06.2017
IPC:
A61K 35/545 (2015.01) ,A61P 1/00 (2006.01) ,A61P 1/16 (2006.01) ,A61P 5/00 (2006.01) ,A61P 9/00 (2006.01) ,A61P 11/00 (2006.01) ,A61P 13/00 (2006.01) ,A61P 15/00 (2006.01) ,A61P 17/00 (2006.01) ,A61P 25/00 (2006.01)
Applicants: TOHOKU UNIVERSITY[JP/JP]; 2-1-1, Katahira, Aoba-ku, Sendai-shi, Miyagi 9808577, JP
LIFE SCIENCE INSTITUTE, INC.[JP/JP]; 1-1, Marunouchi 1-chome, Chiyoda-ku, Tokyo 1008251, JP
Inventors: DEZAWA, Mari; JP
UNNO, Michiaki; JP
YAMAMOTO, Toshihiro; JP
SHINDO, Yasuhiro; JP
HARA, Hiroto; JP
MASUTOMI, Naoya; JP
Agent: SANUKI, Shinichi; JP
NIWA, Takeshi; JP
Priority Data:
2016-13207501.07.2016JP
Title (EN) PROPHYLACTIC OR THERAPEUTIC AGENT FOR ORGAN FIBROSIS
(FR) AGENT DE TRAITEMENT PROPHYLACTIQUE OU THÉRAPEUTIQUE POUR LA FIBROSE DES ORGANES
(JA) 臓器線維症の予防または治療剤
Abstract: front page image
(EN) The present invention addresses the problem of providing a safe and easy-to-prepare cell preparation for prevention and/or treatment of organ fibrosis such as liver fibrosis. Provided is a cell preparation for prevention and/or treatment of organ fibrosis such as liver fibrosis, the cell preparation including a SSEA-3-positive pluripotent stem cell (Muse cell) derived from a vital mesenchymal tissue or a cultured mesenchymal cell.
(FR) La présente invention traite le problème consistant à fournir une préparation cellulaire sûre et facile à préparer pour la prévention et/ou le traitement de la fibrose des organes tels que la fibrose hépatique. La présente invention concerne une préparation cellulaire pour la prévention et/ou le traitement d'une fibrose d'organe telle qu'une fibrose hépatique, la préparation cellulaire comprenant une cellule souche pluripotente positive à SSEA-3 (cellule MUSE) dérivée d'un tissu mésenchymateux vital ou d'une cellule mésenchymateuse en culture.
(JA) 本発明は安全かつ調製が容易な、肝線維症などの臓器線維症の予防及び/又は治療のための細胞製剤を提供することを課題とし、生体の間葉系組織又は培養間葉系細胞に由来するSSEA-3陽性の多能性幹細胞(Muse細胞)を含む、肝線維症などの臓器線維症を予防及び/又は治療するための細胞製剤を提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)