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1. (WO2018003988) NUCLEIC ACID AND COMPOSITION FOR TREATING TUMORS, INCLUDING BRAIN TUMORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/003988    International Application No.:    PCT/JP2017/024223
Publication Date: 04.01.2018 International Filing Date: 30.06.2017
IPC:
A61K 48/00 (2006.01), A61K 31/712 (2006.01), A61K 31/713 (2006.01), A61P 35/00 (2006.01)
Applicants: PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY [JP/JP]; 1, Aza Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya-shi, Aichi 4678601 (JP).
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY [JP/JP]; 1, Furo-cho, Chikusa-ku, Nagoya-shi Aichi 4648601 (JP).
THE UNIVERSITY OF TOKYO [JP/JP]; 3-1 Hongo 7-Chome, Bunkyo-Ku, Tokyo 1138654 (JP).
THE UNIVERSITY OF TOKYO [JP/JP]; 3-1 Hongo 7-Chome, Bunkyo-Ku, Tokyo 1138654 (JP)
Inventors: KONDO Yutaka; (JP).
DEGUCHI Shouichi; (JP).
NATSUME Atsushi; (JP).
KATSUSHIMA Keisuke; (JP).
MIYATA, Kanjiro; (JP).
KATAOKA, Kazunori; (JP).
NAITO, Mitsuru; (JP).
MIYATA, Kanjiro; (JP).
KATAOKA, Kazunori; (JP)
Agent: HIRAKI & ASSOCIATES; Atago Green Hills MORI Tower 32F, 5-1, Atago 2-chome, Minato-ku, Tokyo 1056232 (JP)
Priority Data:
2016-131073 30.06.2016 JP
Title (EN) NUCLEIC ACID AND COMPOSITION FOR TREATING TUMORS, INCLUDING BRAIN TUMORS
(FR) ACIDE NUCLÉIQUE ET COMPOSITION PERMETTANT LE TRAITEMENT DE TUMEURS, Y COMPRIS DE TUMEURS DU CERVEAU
(JA) 脳腫瘍を含む腫瘍の治療用核酸および組成物
Abstract: front page image
(EN)This application provides a pharmaceutical composition for treatment or prevention in a subject having a tumor that expresses the LINC00461 gene characterized by including as an active ingredient a nucleic acid that suppresses the expression of the LINC00461 gene, and an antitumor nucleic acid that suppresses the expression of the LINC00461 gene.
(FR)L'invention concerne une composition pharmaceutique permettant le traitement ou la prévention chez le patient atteint d'une tumeur exprimant le gène LINC00461, caractérisée en ce qu'elle comprend comme principe actif un acide nucléique qui inhibe l'expression du gène LINC00461, ainsi qu'un acide nucléique antitumoral qui inhibe l'expression du gène LINC00461.
(JA)この出願は、LINC00461遺伝子の発現を抑制する核酸を有効性成分として含むことを特徴とする、該遺伝子を発現する腫瘍を有する被験体を治療または予防するための医薬組成物、ならびに、LINC00461遺伝子の発現を抑制する抗腫瘍性核酸を提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)