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1. (WO2018002937) COMBINATIONS OF BETA-GLYCOLIPIDES AND 4-[(2-AMINO-3,5-DIBROMOPHENYL)METHYLAMINO]CYCLOHEXAN-1-OL, COMPOSITIONS AND USES THEREOF IN THE TREATMENT OF DISORDERS ASSOCIATED WITH PROTEIN MISFOLDING AND PROTEIN AGGREGATIONS

Pub. No.:    WO/2018/002937    International Application No.:    PCT/IL2017/050730
Publication Date: Fri Jan 05 00:59:59 CET 2018 International Filing Date: Fri Jun 30 01:59:59 CEST 2017
IPC: A61K 31/137
A61K 31/715
A61K 31/7028
A61K 31/7032
Applicants: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED
SHAARE ZEDEK SCIENTIFIC LTD.
Inventors: ARKADIR, David
ILAN, Yaron
ZIMRAN, Ari
Title: COMBINATIONS OF BETA-GLYCOLIPIDES AND 4-[(2-AMINO-3,5-DIBROMOPHENYL)METHYLAMINO]CYCLOHEXAN-1-OL, COMPOSITIONS AND USES THEREOF IN THE TREATMENT OF DISORDERS ASSOCIATED WITH PROTEIN MISFOLDING AND PROTEIN AGGREGATIONS
Abstract:
The present invention provides therapeutic combinations of beta-glycolipides and 4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol, as well as compositions, kits and methods using the same in treating disorders associated with protein misfolding and for immunomodulation.